Module 19 Obstetric & Pediatric Flashcards
What lung volume decreases during pregnancy? By how much
FRC decreases 20%
Is MAC increased or decreased during pregnancy
Decreased by 1/3
Does pregnancy mimic an obstructive or restrictive defect
Restrictive FEV1/FVC is normal
When is cardiac output greatest with pregnancy
After delivery for next few weeks
What hematologic changes are seen in pregnant patient
Plasma volume increases 25-40% leading to dilutional anemia
Pregnancy effects on coagulation
Accelerated but compensated coagulation
Increased platelet turnover
Increased clotting
Increased fibrinolysis
At term uterine blood flow is how much of cardiac output
10%
Painless vaginal bleeding during second or third trimester associated with
Placenta prevails
Painful vaginal bleeding is associated with
Placental abruption
Placenta invades and is confined to the myometrium
Placenta increta
Placenta adheres to myometrium without invasion or passage through uterine muscle
Placenta accreta
Placenta invades and may penetrate the myometrium, uterine serous, or other pelvic structure
Placenta percreta
AFE treatment
Atropine
Ondansetron
Ketorolac
PIH combined with new onset proteinuria after 20 weeks gestation
Pre-eclampsia
Hallmark of preeclampsia
Abnormal placental implantation
Definitive treatment for preeclampsia
Delivery of fetus
Drug of choice for preeclampsia and eclampsia
Magnesium sulfate
Preeclampsia in presence of seizures
Eclampsia
HELLP stands for
Hemolysis
Elevated Liver Enzymes
Low Platelets
Drug shown to improve maternal outcome in HELLP
Dexamethasone 10mg every 2 hours increases number of platelets
Magnesium sulfate dosing for preeclampsia/eclampsia
4-6g over 30 minutes followed by infusion 1-2g/hr
Normal magnesium level
1.8-2.5mg/dL
Loss of DTR at what magnesium level
7-12 mg/dL
Deceleration indicated head compression
Early deceleration
Deceleration indicated cord compression
Variable deceleration
What is the rule of 60s
Variable deceleration associated with fetal asphyxia if fetal HR decreases by 60bpm, greater than 60 seconds, persists for more than 60 seconds
Deceleration indicating uteroplacental insufficiency and fetal compromise. Occurs at peak of contraction
Late deceleration
BAD
How does maternal blood circulate through the placenta
Uterine arteries (2) in Spurted into intervillous space Passes fetal villi Drains back into urethane vein
Uterine blood flow formula
UBF = (Uterine MAP - Uterine vein pressure) / uterine vascular resistance
Predominant adrenergic receptor in Uterine vasculature
Alpha adrenergic receptors
3 factors that decrease uterine blood flow
Maternal hypotension
Uterine vasculature vasoconstriction (Neo)
Uterine contraction
Fetal bradycardia is defined as
HR < 120
2 signs of fetal hypoxia
Fetal bradycardia
Late deceleration
The amniotic sac has ruptured and is accompanied by bleeding and fetal heart rate deceleration. What should you suspect?
Vasa previa
Fetal vessels implanted over cervical os and not protected by placenta or umbilical cord
CAN LEAD TO EXSANGUINATION OF FETUS
Classic presentation of AFE
Dramatic and abrupt onset of dyspnea and hypotension
Coagulopathy near delivery
Cardiovascular collapse
Oxytocin should be avoided in what 3 groups of patients
Preeclampsia
HTN
Cardiac disease
Oxytocin MOA
Side effects
Acts on uterine smooth muscle to stimulate frequency and force of contraction
Increase in BP and HR
antidiuretic effect leads to water intoxication, cerebral edema, and convulsions
Tocolytic MOA
Name 2
Suppress uterine contractile activity
Ritodrine
Terbutaline
Formula for ETT size in children over 2
(16 + age)/4
Formula for ETT depth
ETT internal diameter x 3
Normal SBP formula children >1yo
(Age x2) + 70
EBV premie
90-100ml/kg
EBV term newborn
80-90ml/kg
EBV 3mo to 3yo
75-80ml/kg
EBV 3-6yo
70-75ml/kg
EBV >6
65-70ml/kg
EBV obese
50-55ml/kg
Congenital diaphragmatic hernia most common at what site
Left foramen of Bochdalek
Goal in treatment of congenital diaphragmatic hernia
Preductal sat >85% with PIP <25cmH20
Avoid N20
Most common variation of TEF
Ends in a blind pouch and lower esophagus that connects to trachea
Intubation technique for TEF
Intentionally mainstem then withdraw until bilateral breath sounds. Tip distal to TEF (between TEF and carina)
Nonbilious projectile vomiting at 2-5 weeks of age associated with
Pyloric stenosis
Classic metabolic disturbance with pyloric stenosis
Hypokalemic, hypochloremic metabolic alkalosis with compensatory respiratory acidosis
Bilious vomiting is classic sign of
Intestinal malrotation and volvulus
How to mix racemic epi new
2.25% solution. 0.5-1ml in 2-3 ml NS
Repeat in 20 minutes and every 2-4 hours PRN
APGAR score 0-2 action
Intubate and CPR
APGAR 3-4 action
Temporary ventilation assistance
APGAR 5-7 action
Stimulation and oxygen across face
Normal HR and RR for newborn
RR 30-60
HR 120-160
Hallmark of intravascular fluid depletion in neonates is
Hypotension without tachycardia
Two limitations of kidney function in newborn
Obligate sodium excreters
Diminished ability to concentrate urine
When is cytochrome P450 enzyme system fully functional
1 month old
Hemoglobin concentration drops after birth when/to what
9-12 weeks reaching 10-11g/dL
When does hemoglobin stabilize
12 weeks until 2 years 11.5-12g/dL
What is the caloric need in relation to BSA for full term infant
30kcal/m2 per hour
By 2 yo 50kcal/m2 per hour
Resting 02 consumption for infant
6-8ml/kg/min
Where are pulse oximetry placed to monitor preductal and postductal saturation
Preductal right hand
Post ductal left foot
Preductal pulse ox used to monitor
Cerebral oxygenation
Postductal sat monitor monitors what
Quantitative severity of left to right shunt
What causes foramen ovale to close
Decrease in PVR and increased pulmonary flow
Increased pressure in LA shuts the flap
What closes the ductus arteriosus
Increased arterial oxygen tension and decreased circulating prostaglandins
4 factors that may cause infant to return to fetal circulation
Hypothermia
Hypercarbia
Acidosis
Hypoxemia
Increased PVR and R-L shunting
Congenital defects in which there is a simple right to left shunt
TOF
Pulmonary atresia
Epstein’s anomaly
Eisenmenger’s syndrome
Congenital defects in which there is a simple left to right shunt
ASD VSD AV canal defect PDA Aortopulmonary window
Conditions that increase PVR
Hypoxia Hypercarbia Acidosis Hypothermia High mean airway pressures Catecholamine release Medications (neo, ketamine, N20) Decreased SVR B2 agonists Neuraxial Deep general anethesia
Congenital defects seen with tetralogy of fallot
VST
RVOT
RV hypertrophy
Overriding aorta
Mandibular hypoplasia is associated with what congenital diseases
Pierre Robin
Treacher Collins
Goldenhar
What are the causes of retinopathy of prematurity
Oxygen toxicity
Prematurity (PCA <32 weeks)