Module 2: Renal, Fluid & Lyte, Acid-Base Flashcards
Reabsorbed the bulk of filtered fluid and dissolved constituents.
Coarse control mechanism for renal regulation of ECF volume and composition
Proximal tubule
Establishes and maintains osmotic gradient in medulla of kidney. Aka countercurrent multiplier
Loop of Henle
Reabsorption of water is under control of
ADH
Reabsorption of sodium and secretion of potassium is under control of
Aldosterone
The action of hormones alter the function of which part of kidney
Distal tubule and collecting duct
Vasopressin (ADH) is synthesized where
Stored where
Acts where
Synthesized: peraventricular and supraoptic nuclei in hypothalamus
Stored in posterior pituitary
Actors on collecting ducts
Posterior pituitary is aka
Neurohypophysis
67% of filtered water is reabsorbed from the ________
13% from ______
67% from proximal tubule
13% from descending limb of loop of Henle
Aldosterone is produced where
Zona glomerulosa of adrenal cortex
Aldosterone acts on which part of kidney
Late distal tubule and collecting duct
Increases rate of Na+ reabsorption
And increases rate of K+ secretion into late distal tubule
Loop diuretics work where
Inhibit reabsorption of Na-K-Cl from ascending limb of loop of henle
Lasix, bumex, demadex
Thiazides diuretics and potassium sparing diuretics work where
Inhibit dosing reabsorption in early distal tubule (also decreases K+ secretion)
Carbonic anhydride inhibitor diuretics work where
Inhibition in proximal tubule inhibits bicarb reabsorption and decreases sodium reabsorption causing diuresis
Best test for distinguishing prerenal failure from renal failure (ATN)
Fractional exertion of filtered sodium
Hyperkalemia causes what EKG changes
Peaked T
Prolonged PR
Widened QRS
