Module 2 Exam 1 Lecture 1 Flashcards

1
Q

A1c tx goal for geriatrics

A

7-8%

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2
Q

What is a key assumption that is made when treating a patient with chronic medical condition

A

low life expectancy

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3
Q

How long of a treatment of diabetes treatment is needed to avoid organ failure

A

10 years

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4
Q

How do we treat diabetic patients for patients that have a chronic medical condition with low life expectancy

A

Control for hypoglycemia, while treating the polyuria and polydipsia

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5
Q

Why are sulfonylureas not 1st line for older adults

A

Due to risk of hypoglycemia, older adults are more likely to experience side effects
Also more likely to experience falls and CVD death relative to younger adults

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6
Q

common geriatric syndromes

A

Sensory impairment (vison and hearing)
Incontinence
Constipation
Poor nutrition
depression
insomnia
Poverty
falls
Delirium
Dementia
Weakness
Immobility

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7
Q

What are the two functional categories of abilities in older adults

A

ADLs and IADLs
(activity of daily living vs Instrumental activities for daily living)

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8
Q

What are some ADLs

A

Dressing
bathing
feeding
toileting
walking/ambulation

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9
Q

What are some IADLs

A

Handling finances
shopping for groceries
meal preparations
using a telephone
house keeping/laundry
handling meds
using transportation

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10
Q

What are some medications that can cause a risk of falls

A

Sedative/hypnotics
Neuroleptics/antipsychotics
antidepressants
opioids
loop diuretics
alpha blockers

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11
Q

What is the beers criteria

A

Because of age, relative to a younger population, are you at a higher risk of adverse medical conditions

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12
Q

What are 3 medication problems in older adults

A

Polypharmacy
Non-adherence
PK changes with aging

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13
Q

Why can polypharmacy be a problem in older adults

A

Multiple medications without an indication
Medications treating ADRs

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14
Q

Older patients are more adherent to meds than younger ones

A

TrueW

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15
Q

What are some physiologic changes that occur when we age that can affect the PK of drugs

A

Decrease in TBW
Decrease in lean body mass
Increase in body fat
Decrease in baroreceptor response activity (sitting down for 8 hours and standing up dizzy)
decrease in HR variability
Decrease in hepatic blood and renal blood flow
decreased neurotransmitter volume (Increased sensitivity to CNS adverse effects

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16
Q

What happens to tmax in older adults

A

Slows down

17
Q

What happens Vd and concentration of water soluble drugs in older patients

A

decrease in volume of distribution and increase in concentration of drug due to the decrease in total body water. (atenolol)

18
Q

What happens to Vd and t1/2 of lipid soluble drugs in older patients

A

Increased Vd and increased t1/2 of lipid soluble drugs (rifampin)

19
Q

what happens to clearence and t1/2 of hepatically cleared drugs in older patients

A

Decreased clearence and increased t1/2 of most hepatically cleared drugs (propanolol)

20
Q

What happens to clearence and t1/2 of most renally cleared drugs

A

decreased clearence, increased t1/2 of most renally cleared drugs

21
Q

beers criteria is for adults aged above

A

65 and up

22
Q

Which type of medications should we evaluate risks for in older adults

A

Meds with anticholinergic properties
Sedatives with CNS effects
Diabetic agents

23
Q

What should we focus on when assesing risk of anticholinergic agents in older adults

A

Focus on risk of cognitive impairment

24
Q

What should we focus on when assessing risk of diabetic drugs in older adults

A

Sliding scale insulin, long acting sulfonylureas

25
Q

Beers criteria diabetes drugs

A

Sulfonylureas (glipizide, glyburide, glimepride)
SGLT2s (flozins)Sliding scale insulin)

26
Q

What is a big recommendation for rational prescribing

A

recognize new symptoms as potential adverse rxns

27
Q

considerations in choosing medications

A

Remaining life expectancy
time to benefit
Goal of care
Tx targets

28
Q

What is palliative care

A

after diagnosis of terminal illness, disease not responsive to curative tx or tx does not exist

29
Q

What are some goals for palliative care

A

Optimize QOL and focus on sx only not on prolonging life
stop meds not improving QOL

30
Q

What is hospice care

A

provides at home facility. Life expectancy is 6 months or less

31
Q

Does beers criteria apply to palliative or hospice care?

A

no

32
Q

What does ACD stand for

A

advanced care directives

33
Q

what is an ACD

A

Verbal and written instructions about future medical care and tx (allows you to make a choice of if I am in a life threatining situation, do I want chest compressions, intubated? ETC…)

34
Q

ACDs include

A

healthcare representatives- names someone to make decisions in patient is not able

psychiatric advanced directives- sets preferences during periods of incapacity

power of attorney- financial or healthcare power to other people you choose

35
Q
A