Module 2 Flashcards
propulsion
movement of food through gi tract- peristalsis
secrretion
release of enzymes
segmentation
back and forth churning of food in small intestine
layers of gi tract
mucosa - inner
sub mucosa
muscularis
tunica serosa - outer
parietal peritoneum
lines body wall
visceral peritoneum
lines organs
retroperitineal
outside cavity
intraperitoneal
within cavity, in a glad wrap sack
mesentary
contains blood and lymph vessels an veins
stomach mesentaries
lesser, greater (outside curve)
stomach sphincters
pylorus
rugae
folds in stomach (grooves)
blood supply of GI tract
celiac trunk- sup meseneric artery - inf mesenteric artery
unpaired organs get blood from
unpaired blood vessels
celiac trunk blood supply
liver, stomach and spleen
sup mesenteric artery blood supply
duodenum and pancreas
inf mesenteric artery blood supply
sigmoid colon, upper rectum
duodenum function
mixing bowl, has pancreas, entry point for bile and pancreatic juice
jejinum fuction and where it starts
absorption, starts at duodeno-jejunal flexure
ileum function
absorbs B12, salts and things not already absorbed
3 circular folds
villi, microvilli and plicae
circular folds functions
increase SA for nutrient absorption
slows food passage
large intestine function
water and electrolyte absorption
makes faeces
conatins 4 colons
liver functions
secretes plasma proteins stores fat soluble vitamins makes bile breaks down chyme aids fat digestion
liver blood supply
gets O2 rich and O2 poor blood
ligaments in liver
coronary - suspends diaphragm from liver
and faliciform - secures liver to abdominal wall
4 liver lobes
right ( bare area), left, quadrant an caudate
gallbladder
concentrates bile an stores it
pancreas functions (exo and endo)
exocrine- produces pancreatic juice
endocrine - produces insulin ans glucagon
enzymatic breakdown
Mechanism of digestion
mechanisms of absorption
involve materials passing through enterocytes (active or passive)
monosaccharides
glucose, fructose,galactose
disaccharides
sucrose, lactose, maltose
Polysaccharides
starch,
non-starch
Amylase
acts on polysaccharides
& disaccharides
Disaccharidases
act on disaccharides
(maltase,
sucrase, lactase)
fibre
cant be absorbed but helps move food along GI tract and feed bacteria in large intestine
Pepsin
acts on proteins
Pancreatic proteases
act on
protein
fragments
Aminopeptidases
act on protein
fragments
Proteins must be digested into
small peptides or amino acids before they can
be absorbed
Fats
- Triglycerides
– Sterols
– Short-chain fatty acids
Triglycerides must be digested into
monoglycerides or fatty acids before they can be absorbed
Lipase
acts on triglycerides
Emulsification
Bile salts break down large fat globules into smaller fat
droplets, increasing surface area for lipase enzymes
Micelle formation.
Free fatty acids and monoglycerides join bile salts
forming micelles
Kidneys
filter waste products from
the bloodstream & convert the filtrate
into urine
Ureters
transport urine from kidney
to bladder via peristalsis
Urinary bladder:
storage of urine
Urethra
transports urine from
bladder to outside of the body
Function of kidney
regulation of blood volume, regulation of bloods ion balance, acid base balance
renal fascia
dense irregular
tissue; anchors the kidney to
surrounding tissues
adipose capsule
fat with
adipose tissue: cushioning
and insulation
renal capsule
dense connective
tissue: maintains kidney shape;
protects from pathogens
urine transport pathway
minor calices, major calices, renal pelvis and ureter
arteries of kidney
RSIAI- Renal artery Segmental artery Interlobar artery Arcuate artery Interlobular artery
renal corpuscle
produces a filtrate of blood and is composed of a capillary network called the glomerulus
glomerulus
surrounded by the glomerular capsule (Bowman capsule)
Ureter layers
mucosa, muscularis, adventina
urinary bladder trigone
triangular area of urinary bladder. functions as a funnel to direct urine to urethra
Internal urethral
sphincter
prevents the simultaneous passage of sperm and urine through the male urethra
Glomerular filtration
filters the blood- produces a cell-and protein-free
filtrate
Tubular reabsorption
selectively
moves substances from the filtrate
back into the blood to reclaim what the
body needs
Tubular secretion
selectively adds
substances from the blood into the
filtrate
Hydrostatic pressure
forces fluids & solutes
through a membrane
Glomerular filtration rate (GFR)
volume of filtrate formed
each minute by the kidneys
Countercurrent multiplier
interaction between flow of filtrate through
ascending & descending nephron limbs
establishes the gradient
Countercurrent exchanger
flow of blood through ascending & descending portions
of vasa recta preserves the gradient
what creates osmotic gradient
nephron loops
Benefits to countercurrent mechanisms
- establishes a vertical osmotic gradient
- allows kidney to excrete dilute urine when dehydrated
Variable water reabsorption is
regulated by
ADH
Vasa recta
preserve the vertical osmotic gradient –
countercurrent exchangers
Nephrons
create the vertical osmotic gradient –
countercurrent multipliers
Distal & collecting tubules
use the vertical osmotic gradient to
adjust urine concentration
Kidney diseases
Acute Kidney Injury , Chronic kidney disease
celiac trunk supplies…
above transverse mesocolon and stomach
kidneys are suspended in:
renal capsule, adipose capsule and renal fascia (inner)
The key processes of urine formation in order of occurrence are
Glomerular filtration, tubular reabsorption, tubular secretion
function of nephron
It’s function is to filter out waste and toxins from the blood, regulate the concentration of water and solutes in blood. Through this it produces urine.
GFR is directly proportional to:
- Net filtration pressure
- Total surface area for filtration
- Filtration membrane permeability
explain ADH action when dehydrated
ADH is released by posterior pituitary upon increase ECF conc. it then promotes the insertion of aquaporins on the distal and collecting tubule, which allows for more water reabsorption and the body can rehydrate itself
what happens when we are overhydrated and have no ADH
Distal and collecting tubules are impermeable to water
explain why osmolarity gradient is important
establishes the gradient to concentrate more urine
allows dilute urine to be excreted
allows for water reabsorption
what is the counter current multipier
loop of henle: flow of filtrate moving opposite directions each side creating the gradient. difference in permeability to water and salt creates a flow and ongoing cycle
whats counter current exchanger
vasa recta blood vessels preserve the concentration gradient
what do distal and collecting tubules do
use the vertical gradient to adjust urine concentration