Module 1 Flashcards
Arteries
Carry blood away from heart
Veins
carry blood to the heart
capillaries
exchange of gases between tissues
pulmonary circuit
blood to lungs
systemic circuit
blood to rest of body
heart is surrounded by
pericardium
layers of pericardium
outer fibrous and inner serous
histology of heart wall
epicardium (outer), myocardium, endocardium (inner)
right ventricle
pumps for low pressure pulmonary circuit
left ventricle
pumps high pressure for systemic circuit
2 preventions of back flow of blood
atrioventricular valves and semilunar valves
systole
contraction
diastole
relaxation
Electrical events of the cardiac cycle
P wave -atrial depolarization
QRS complex -ventricular depolarization & atrial repolarization
T wave -ventricular repolarization
PR interval-AV node delay
ST segment –entire ventricle is depolarized
Cardiac output (CO)
amount of blood pumped out by each ventricle in 1 minute
Layers of arteries and veins
tunica intima, media and externa
Branches of the arch of the aorta
- brachiocephalic trunk
- left common carotid artery
- left subclavian artery
What is the function of blood vessels?
Vascular highways’ that transport blood around the body to meet demands
Arterioles
regulate blood flow into tissues
Venules
carry away waste from tissues
Pulse pressure
difference between systolic & diastolic pressures. It is this pressure difference we can feel when taking our pulse
Mean arterial pressure
the average pressure during each cardiac cycle
MAP =
diastolic pressure + 1/3 (systolic –diastolic)
MAP = CO x TPR
Blood flow to any given organ depends on
- resistance of local arterioles
2. vascularisation/open capillaries
Baroreceptors
regulates short-term responses in MAP
Long-term regulation of MAP
Left atrial volume receptors and Hypothalamic osmoreceptor
nasal septum
central wall of bone dividing the nasal cavity
Lateral wall of nasal cavity + function
conchae- increase the surface area
Pharynx divisions
Nasopharynx: from floor of skull to soft palate,
Oropharynx: from soft palate to hyoid bone
Laryngopharynx: from hyoid bone to oesophagus
Larynx
voice box, connects the pharynx to the trachea
larynx ligaments
Superior (vestibular) ligaments; Vestibular folds: false vocal cords
Inferior (vocal) ligaments; Vocal folds: true vocal cords
Trachea function
filter, warm, humidify air
splits at carina to primary bronchi
The Bronchi branches
Primary bronchus
Secondary bronchus
Tertiary bronchi
Bronchioles
bronchioles branches
terminal bronchioles, respiratory bronchioles, alveolar ducts and alveoli
Pulmonary ventilation and Boyle’s Law
Increasing volume of the thoracic cavity during inhalation decreases intrapulmonary pressure
2 Pleura cavities
visceral (no pain) and parietal (pain)
Breathing types
Eupnea - quiet
hypereunpea - fast forced
Goblet cells produce?
mucin an mucous glands
venous return
volume of blood returning to heart each minute
blow flow is directly proportional to…..
pressure gradient
korokoff sounds
turbulent sounds of blood flow
diastole is pressure ______ the cuff
below
systole is pressure _____ the cuff
above
airflow is directly proportional to
pressure gradient
alveolus
gas filled air space
surfactant
mixture of detergent like liquids that decrease water cohesiveness and reduce surface tension
premature babies lack_____
surfactant - alveoli may collapse between breaths
compliance
stretchy
lung compliance is determined by
distensibility of lung tissue
alveolar surface tension
respiratory volumes
tidal
inspiratory
expiratory
residual
respiratory capacities
inspiratory
functional residual
vital
total
dead space
air never used in gas exchange
2 ventilation types
pulmonary
alveolar
spirometry
lung function test used to differentiate between obstructive and restrictive lung diseases
gas exchange by diffusion
- partial pressure gradient
- thickness and surface area
- ventilation and perfusion
2 forms of oxygen transport
- bound to haemoglobin
- dissolved in plasma
haemoglobin contains…
4 oxygen molecules
loading and unloading is regulated by:
partial pressure
temperature
blood hydrogen levels
3 ways of Carbon dioxide transport
dissolved in plasma
bound to haemoglobin
as bicarbonate ions in plasma
Amount of CO2 transported is affected by
02 levels
2 neural mechanisms
medullary respiratory
pons respiratory
medullary respiratory 2 neural clusters
ventral and dorsal respiratory group
pons respiratory
fine tune breathing during activity
what has greatest influence on respiration and ventilation
CO2
breathing during exercise can be caused by,
psychological anticipation of exercise
motor activation
Lung diseases
asthma, bronchitis, TB, cancer, sleep apnea
Which vessel brings blood directly into the right atrium?
superior vena cava
atrioventricular (AV) valve
prevents blood from flowing back into the left atrium
During the period of ventricular filling, ________.
blood flows mostly passively from the atria through the atrioventricular (AV) valves into the ventricles
blood vessel resistance is determined by
blood vessel radius
inspiratory reserve volume
The amount of air that can be inspired above the tidal volume
Which determines the direction of respiratory gas movement?
partial pressure gradient
The receiving chambers of the heart
right and left atria
foramen ovale
connected the two atria in the fetal heart
which ligament produces sounds
vocal ligament
Expain how the respiratory system can function to influence acid balance
When we exhale carbon dioxide it has the ability to neutralise the pH in our body, if carbon dioxide remained in our body for too long it will mix with water and produce hydrogen ions that drop the pH in our body.
what to goblet cells produce
mucin- humidifies air
During inspiration the volume of the lungs expands which causes pressure in the alveoli to
become lower than the atmospheric pressure
3 things that affect air flow
- Resistance of airway passages
- Alveolar surface tension and surfactant
- Lung compliance
What are the three main factors that affect gas exchange?
- Partial pressure gradient
- Thickness and surface area of exchange membranes
- Ventilation-perfusion coupling
What are some ways that haemoglobin loading and unloading is regulated by?
- Partial pressure of oxygen
- Temperature
- Hydrogen ions
What are the three ways that carbon dioxide is carried in blood?
- Dissolved in plasma
- Bound to haemoglobin within red blood cells
- As bicarbonate ions in plasma
2 left & 2 right pulmonary veins
from each lung carry
oxygen rich (oxygenated) blood to the left atrium
1 left & 1 right pulmonary
artery carry
oxygen poor (deoxygenated) blood to each lung
Right ventricle pumps into
Pulmonary trunk
what vessel supplies the heart with blood
coronary arteries
how does blood get back to the heart
through superior vena cava
coronary circulation
hearts own blood supply
list bloow flow through heart
(blue) SUP + INF vena cava, RA, RV, pulmonary trunk…
to lungs..
(red) in through 4 pulmonary veins, LA, LV, Aorta
fissures in left lung
oblique
fissures in right lung
oblique and horizontal (3 lobes)
muscles used in quiet breathing
diaphragm, ext intercostals
muscles used in forced breathing
accessory and int intercostals
mechanical phases of cardiac cycle
- ventricular filling
- isovolumetric contraction
- ventricular ejection
- isovolumetric relaxation
pressure changes in in cardiac cycle
valves open when pressure is higher in first compartment.
valves close when pressure is higher in next compartment. (direction of blood flow).
partial pressure gradient
difference in partial pressure between blood &
surrounding structures