Module 11 ML-4 Flashcards

1
Q

How much of o2 is dissolved in the blood`

A

1.5%

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2
Q

How much blood is bound to hemoglobain

A

98.5% due to its low solubility

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3
Q

How many oxygen molecules can bind to one hemoglobin subunit?

A

4

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4
Q

TRUE OR FALSE; once o2 is bound to hemoglobin is does not contribute ti partial pressure

A

true

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5
Q

Diffusion of o2 is due to what

A

the partial pressure gradient

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6
Q

what happens when there is small changes of pp of oxygen from 120-60

A

there isn’t that much change in hemoglobin

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7
Q

What happens when hemoglobin comes across low pp of o2

A

it unbunds the o2 so the oxygen can go where it is needed

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8
Q

what is the perctange of bound hemoglobin in the systemic arteries

A

98%

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9
Q

what is the percentage of bound hemoglobin in systemic venous

A

75%

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10
Q

How does o2 move into the capillary

A
  1. dissolved o2 flows in which increased pp so o2 flows into rbc which increased pp and then hemoglobin and o2 can bind
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11
Q

How does o2 move out of the capillary

A

oxygen moves into intersitial fluid and then into cytosol and then into mitochondria which lowes pp and then causes the hemoglobin to unbind

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12
Q

as temp increases what happens to the hemoglobin

A

it loses the affinity for o2 and starts to unbind

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13
Q

as temp decreases what happens to the hemoglobin

A

it stops hemoglobin from unbinding from o2

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14
Q

What happens to hemoglobin when you have high acidity, low ph, imcreased co2

A

decrease affintiy

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15
Q

what happens to hemoglobin when you have low acidity, high ph, low co2`

A

increase affinity

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16
Q

left shifted means

A

o2 binding promoyted

17
Q

right shifted means

A

02 release promoted

18
Q

what happens when co is bound to hemoglobin

A

the o2 carrying capacity is low and o2 struggle to unbind to hemoglobin

19
Q

What are the two dangerous effects of hemoglobin

A

it reduces content of o2 in the blood and it shifts the o2 hb curve to the left (harder to unload o2)

20
Q

Why with co posioning do you suffocate without knowing

A

because po2 looking normal to chemoreceotors

21
Q

What is anemia

A

a decrease in hemoglobin concentration of the blood which reduces o2 carrying capcity of the blood