Module 11 ML-4 Flashcards
How much of o2 is dissolved in the blood`
1.5%
How much blood is bound to hemoglobain
98.5% due to its low solubility
How many oxygen molecules can bind to one hemoglobin subunit?
4
TRUE OR FALSE; once o2 is bound to hemoglobin is does not contribute ti partial pressure
true
Diffusion of o2 is due to what
the partial pressure gradient
what happens when there is small changes of pp of oxygen from 120-60
there isn’t that much change in hemoglobin
What happens when hemoglobin comes across low pp of o2
it unbunds the o2 so the oxygen can go where it is needed
what is the perctange of bound hemoglobin in the systemic arteries
98%
what is the percentage of bound hemoglobin in systemic venous
75%
How does o2 move into the capillary
- dissolved o2 flows in which increased pp so o2 flows into rbc which increased pp and then hemoglobin and o2 can bind
How does o2 move out of the capillary
oxygen moves into intersitial fluid and then into cytosol and then into mitochondria which lowes pp and then causes the hemoglobin to unbind
as temp increases what happens to the hemoglobin
it loses the affinity for o2 and starts to unbind
as temp decreases what happens to the hemoglobin
it stops hemoglobin from unbinding from o2
What happens to hemoglobin when you have high acidity, low ph, imcreased co2
decrease affintiy
what happens to hemoglobin when you have low acidity, high ph, low co2`
increase affinity
left shifted means
o2 binding promoyted
right shifted means
02 release promoted
what happens when co is bound to hemoglobin
the o2 carrying capacity is low and o2 struggle to unbind to hemoglobin
What are the two dangerous effects of hemoglobin
it reduces content of o2 in the blood and it shifts the o2 hb curve to the left (harder to unload o2)
Why with co posioning do you suffocate without knowing
because po2 looking normal to chemoreceotors
What is anemia
a decrease in hemoglobin concentration of the blood which reduces o2 carrying capcity of the blood
