Module 10 Flashcards
Tissue
A collection of cells that work together to perform a specific function.
Cell Junctions
A complex of proteins in the cell membrane where a cell makes contact with another cell or the extracellular matrix (physically connect one cell to the next and anchor cells to the extracellular matrix).
Microfilaments
A double helix of actin monomers. Smallest diameter. Maintain cell shape and used in muscle cell contractions.
Intermediate Filaments
A strong fiber composed of intermediate filament protein subunits. Medium diameter. Provide cells with mechanical strength.
Alpha Tubulin
One half of a tubulin dimer.
Beta Tubulin
One half of a tubulin dimer.
Dynamic Instability
Cycles of polymerization and depolymerization in microtubules.
Motor Proteins
Any of various proteins that are involved in intracellular transport or cause muscle contraction by moving the actin microfilaments inside the muscle cells (small accessory proteins).
Cell Adhesion Molecules
Allow cells to attach to other cells and to the extracellular matrix.
Integrins
Integral transmembrane glycoproteins for cells to attach to ECM. Occurs between the cell and the ECM. Attaches to the cytoskeleton.
Adherens Junction
A beltlike junctional complex composed of cadherins that attaches a band of actin to the cell membrane (goes around the circumference of the cell).
Hemidesmosome
A type of cell junction that anchors cells to the extracellular matrix (like desmosomes but use integrins not cadherins).
Gap Junction
A type of connection between the cell membranes of adjacent animal cells that permits material to pass directly from the cytoplasm of one cell to the cytoplasm of another (cell-to-cell communication).
Extracellular Matrix (ECM)
A meshwork of proteins and polysaccharides outside animal cells. The main constituent of connective tissue. For plants it is the cell wall and for animals it is abundant connective tissue. Influence the shape of the cells and the gene expression of the cells.
Laminin
A fibrous protein present in the basal lamina of the epithelia.
Cytoskeleton
An internal protein scaffold that helps cells to maintain their shape and serves as a network of tracks for the movement of substances within cells.
Microtubules
A hollow tube formed from tubulin dimers (α and β). Largest diameter. Maintain cell shape and make up spindles in cell division.
Actin
A protein that forms microfilaments. It associates with the motor protein myosin in muscles to contract and generate force.
Centrosome
A compact structure that is the microtubule organizing center for animal cells.
Myosin
A motor protein found in cells that carries cargo to the plus ends of microfilaments and is also used by both striated and smooth muscles to contract and generate force.
Kinesin
Moves the cargo towards the microtubule’s plus end.
Dynein
Moves the cargo towards the microtubule’s minus end.
Cadherins
Integral transmembrane glycoproteins for cell-to-cell attachment. Occurs in the extracellular domain. Attaches to the cytoskeleton.
Anchoring Junctions
Connect adjacent cells and are reinforced by the cytoskeleton.
Desmosomes
A buttonlike cell junction that holds the cell membranes of adjacent cells together (specific spots of dense clusters of cadherins).