(Module 1) Evaluation of Crude Drugs Flashcards
ensures the identity of a drug and determines the quality and purity of drugs
evaluation of a drug
methods:
organoleptic
microscopic
physical
chemical
biological
means the study of drugs using the organs of senses
organoleptic evaluation
initial identification of herbs and identifying small fragments of crude or powdered herbs
detection of adulterants
microscopical evaluation
chemical evaluation
qualitative chemical tests
quantitative chemical tests
chemical assays
instrumental analysis
chemical methods of evaluation
isolation
purification
identification of APIS
identification tests for various phytoconstituents like alkaloids, glycosides, tannins, etc
qualitative chemical tests
acid value
saponification
ester value
acetyl value
quantitative chemical tests
assays for alkaloid, resin, volatile oil, glycoside, vitamins, or other constituents
chemical assays
used to analyze the chemical groups of phytoconstituents using chromatographic and spectroscopic methods
instrumental analyses
paper chromatography, etc.
chromatographic methods
ultraviolet and visible spectroscopy, etc.
spectroscopic methods
specific behaviors towards solvents
solubility
substances that can rotate the orientation of plane-polarized light. such substances are said to be optically active
optical rotation
property of a material that changes the speed of light
refractive index