module 1-1 Flashcards
symbionts that harm or live at expense of host
parasitic organisms
microbes frequently found on or within bodies of healthy people
commensal organisms
growth and multiplication of parasite on or within host
infection
disease resulting from infection
infectious disease
any parasitic organism that causes infectious disease
pathogen
causes disease by direct interaction with host
primary (frank) pathogen
causes disease by disease only under certain circumstances
opportunistic pathogen
ability of parasite to cause disease
pathogenicity
any component of a pathogenic microbe that is required for or that potentiates its ability to cause disease
virulence factor
steps in an infectious disease:
- encounter
- entry
- spread
- multiplication
- damage
- outcome
- encounter
exogenous
endogenous
congenital
- entry
via ingress: inhalation or ingestion
or penetration: microbes pass thru directly (like blood transfusions or insect bites)
lateral propagation vs. dissemination
anatomical factors
active participation by microbes
- spread
environmental factors (like temp)
subversion of host defenses
(cell division)
- multiplication
immune response
- damage
(direct damage)
microbe wins, host wins, or they learn to coexist
- outcome
microbes frequently found on or within the bodies of healthy persons
normal microbiota (commensal organisms)
colonization by bacterial occurs rapidily after _____
birth
microorganisms of the human body
bacteria
virus
fungi
protozoa
(helminths aka worms)
locations in the body with largest amount of bacteria
skin
respiratory tract
digestive tract
urinary tract
genital system
body locations that are sterile
blood
cerebrospinal fluid
synovial fluid
deep tissue
examples where normal flora are source of the infection
periodonitis
pneumonia
catheter infections
issues for microbial cells
nutritional fluxes
mantaining occupancy
resistance to damage
saliva:
-inorganic, organic, glycoproteins and proteins
-promotes adhesion of bacteria on teeth (salivary pellicle)
-source of food
maintains pH!!!!
-inhibits growth of microbes
factors that modulate oral microbial growth:
saliva
GCF
anatomical features that create areas that are difficult to clean
microbial factors
local pH
diet
redox potential
antimicrobial therapy
iatrogenic factors (scaling)