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microparasitology > Mod 8 micropara lec > Flashcards

Mod 8 micropara lec Flashcards

1
Q

use of chemical in the treatment of disease or condition

A

chemotherapy

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2
Q

chemicals used to treat a disease or condition

A

chemotherapeutic agents

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3
Q

group of agent that share common aim

A

antibiotics

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4
Q

treat fungal infection

A

antifungal

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5
Q

treat protozoal infection

A

antiprotozoal

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6
Q

treat virus infection

A

antiviral agent

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7
Q

treat bacterial infection

A

antibiotics agent

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8
Q

kills & inhibit pathogens
causes no damage to the host
causes no allergic reaction to the host
stable in any form
kills pathogens before they mature and be resistant

A

characteristics of antimicrobial agent

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9
Q

use our own cell machinery

A

viruses

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10
Q

least similar that is related to human

A

prokaryotes

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11
Q

biochemically similar that closely related to humans

A

eukaryotes

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12
Q

antimicrobial that is difficult to develop and use

A

antviral agent

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13
Q

inhibit replication

A

azidothymidine

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14
Q

1st viral agent

A

azidothymidine & zidovudine

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15
Q

treatment for HIV

A

azidothymidine

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16
Q

enzymes synthesized another strand to enter the human cell to facilitates DNA replication

A

reverse transcriptase

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17
Q

selective poision

A

antibiotic

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18
Q

targets either gram positive or gram negative bacteria

A

narrow spectrum

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19
Q

kills gram positive & negative

A

broad spectrum

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20
Q

kills bacteria

A

bacteriocidal

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21
Q

inhibit the growth of bacteria

A

bacterioststic

22
Q

species of fungi

A

penicillium & cephalosporium

23
Q

produce in lab

A

synthetic drug

24
Q

target in bacteria

A

nucleic acid

25
Q

both horizontal and vertical

A

crosslinks

26
Q

inhibit transpeptidase

A

Beta lactam

27
Q

inhibit specific binding of alanine in cross-bridge to transpeptidase

A

vancomycin &cycloserine

28
Q

secretion of NAM & NAG subunits

A

Bacitracin

29
Q

enzyme that is present in almost bacteria

A

Transpeptidase

30
Q

enzyme use to create crosslinks (covalent bonds) between peptidoglycan & cell wall

A

transpeptidase

31
Q

has 2nd 3rd 4th generation

A

cephalosporin

32
Q

disruption of the 50s ribosomes

A

inhibition of protein synthesis

33
Q

change the shape of 30s ribosomes

A

aminoglycosides

34
Q

block assess a site of 30s subunit

A

tetracycline

35
Q

block peptide bind formation from 50s subunit

A

Chloramphenicol

36
Q

block 50s subunit action

A

Macrolides

37
Q

supercoiled maintain by

A

gyrase

38
Q

disrupt bacterial cell membrane

A

polymixin

39
Q

prevent coiling and of DNA

A

Quinolones

40
Q

binds dna block replication

A

metronidazole

41
Q

key of coenzyme

A

follic acid

42
Q

process of inhibition of PABA

A

antimetabolite activity

43
Q

structural analogs of PABA

A

sulfonamides

44
Q

broad range activity against gram positive & negative

A

spectrum of activity

45
Q

combination of sulfonamides & trimethoprim

A

combination therapy

46
Q

prevents emergence of resistant strains

A

combination therapy

47
Q

inhibit formation of tetrahydrofolic acid

A

trimetophrim

48
Q

drug resistant bacteria

A

superbugs

49
Q

explosion of microorganisms due to prolonged used of antibiotics

A

superinfection

50
Q

change in transport protein, ribosome, enzyme

A

mutation

51
Q

conjugation genetic information allowing cell to overcome drug

A

plasmids

52
Q

bacteria learns to use new metabolic pathways

A

end round

microparasitology (7 decks)

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