MOD 6 BIOSAFETY Flashcards

1
Q

intentional release of pathogenic microorganisms aims to protect public health and the environment

A

biosafety

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2
Q

containment controls of biosafety level (principles of laboratory)

A

Laboratory practices
- Safety equipment
- Facility construction

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3
Q

barrier that can use as a personal protective equipment between lab worker and pathogen

A

physical barriers (mga sinusuot)

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4
Q

type of barrier that has structural aspects of the laboratory that make working environment safer against
infection

A

Secondary barriers

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5
Q

replace the hazard

A

substitution

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6
Q

change how people works like social distancing

A

adminstrative controls

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7
Q

refers to the equipment and facility design reduce exposer to the hazard eg; biosafety cabinets

A

engineering controls

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8
Q

physically remove hazard (vaccines)

A
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9
Q

HIERARCHY OF CONTROLS

A

PPE
Administrative controls
engineering controls
substitution
elimination

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10
Q

BSL that has an agents not known to cause disease in healthy adults

A

Biosafety Level 1

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11
Q

agents in Biosafety Level 1

A

Bacillus subtilis, Naegleria
gruberi, infectious canine hepatitis virus,
non-pathogenic E. coli species

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12
Q

Biosafety cabinets that for operation protection (for person only)

A

class 1 Biosafety cabinet

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13
Q

Biosafety cabinets that for protection of spealized laboratory dealing with deadly pathogen

A

class 3

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14
Q

Primary hazards of biosafety level 2

A
  • accidental needle sticks
  • exposure to eyes and nose (mucous membranes)
  • ingestion of infectious material
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14
Q

Biosafety cabinets that for operational and environment is protected also the product

A

class 2

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15
Q

Agents associated with human disease generally required for any human-derived blood, bodily fluids, tissues in which infectious agent may be unknown

A

Biosafety Level 2

16
Q

example agent of a biosafety level 2

A

measles virus, Salmonella
species, pathogenic Toxoplasma, Clostridium botulinum, hepatitis B virus

17
Q

primary hazards of biosafety level 3

A

needle sticks & ingestion exposure to infectious aerosols

17
Q

why does the west nile accur

A

laboratory
worker cut finger while dissecting
bird; 4 days later, had symptoms of fever, myalgia, recurring sweats, hot flashes

17
Q

where does the west nile virus come from

A

birds

18
Q

common source of
laboratory-acquired infection also known as a classified as potential biological weapon

A

tularemia

18
Q

biosafety level with an agents that is potential for respiratory
transmission, may cause serious and potentially lethal infection

A

biosafety level 3

18
Q

practices of biosafety level 2

A

policies to restrict access to lab;
- biohazard warning signs posted
outside lab;
- surveillance of laboratory personnel
with appropriate immunizations
offered;
- biosafety manual with definitions of
needed waste decontamination or
medical surveillance policies;
- supervisory staff who have experience
working with infectious agents and
specific training for laboratory
personnel in handling these agents

19
Q

specific training for lab personnel in handling potentially lethal agents;

A

biosafety level 3

20
Q
A

Corridors separated from direct
access to lab
- Access through self-closing double doors
- Air handling systems to ensure
negative air flow (air flows into the lab)
- Air pumped into lab not re-circulated in building

20
Q
A

Dangerous and exotic agents with high risk of life-threatening disease, aerosol-transmitted

20
Q

acquired virus because of the infected monkeys from uganda

A

Marburg infection in 1960

20
Q

infectious agents of biosafety level 4

A

Ebola virus, viruses that cause
CongoCrimean hemorrhagic fever, Lassa
fever

20
Q

No available vaccines or therapy

A

biosafety level 4

21
Q

secondary barrier of biosafety level 4

A

isolated zone or a separate building;
- dedicated supply and exhaust,
vacuum, decontamination systems;
a recommended absence of windows
(or sealed and resistant to breakage)