MOA of antimicrobials Flashcards

1
Q

glycopeptides

A

cell wall synthesis inhibition

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2
Q

lipopeptides

A

cell wall synthesis inhibition

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3
Q

aminoglycosides

A

binds to 30s

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4
Q

macrolides

A

binds to 50s

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5
Q

lincosamides

A

binds to 50s

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6
Q

tetracyclines

A

binds to 30s

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7
Q

glycylcyclines

A

binds to 30s

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8
Q

fluroquinolones

A

inhibits DNA gyrase and topoisomerase

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9
Q

anti-folates

A

inhibit enzymes in the folate pathways

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10
Q

nitroimidazoles

A

inhibit DNA synthesis

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11
Q

oxazolidinones

A

bind 50s

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12
Q

rifampin

A

binds RNA pol

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13
Q

isoniazid

A

inhibits mycolic acid synthesis

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14
Q

pyrazinamide

A

inhibits mycolic acid synthesis

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15
Q

ethambutol

A

inhibits polymerization of arabinoglycan in mycobacterial wall

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16
Q

penicillins

A

cell wall synthesis inhibitors

17
Q

carbapenems

A

cell wall synthesis inhibitors

18
Q

cephalosporins

A

cell wall synthesis inhibitor