Antibiotics (Class, Spectrum, Common Indications)

Question 1

Penicillin V and Penicillin GSpectrumCommon IndicationsOther

Answer 1

Group: PenicillinSpectrum: Streptococci, Gram +Common Indications: dental infections, endocarditisOther: poor bioavailability

Question 2

Amoxicillin PO and Ampicillin IV

Answer 2

Group: PenicillinSpectrum: Streptococci, enterococcus faecalis, Listeria, Proteus mirabilis, H. influenzaeCommon Indications: otitis media, CAP, enterococcal UTI, enterococcal endocarditisOther

Question 3

Cloxacillin PO/IV

Answer 3

Group: PenicillinSpectrum: methicillin susceptible S. aureusCommon Indications: bacteremia (IV), endocarditis (IV), bone/joint infection (IV)Other: poor bioavailability. PO poorly tolerated

Question 4

Amoxicillin/clavulanate PO

Answer 4

Group: PenicillinSpectrum: G+ and G- enterobacteriaceae, MSSA, Proteus, H. influenzaeCommon Indications: polymicrobial infection (e.g. bite wounds, diabetic foot ulcer)Other: no pseudomonas coverage

Question 5

Piperacillin/tazobactam IV

Answer 5

Spectrum: G+ and G- enterbacteriaceae, MSSA, E. faecalis, pseudomonas, anaerobes.Group: PenicillinCommon Indications: sepsis, polymicrobial infection, intraabdominal infection, febrile neutropeniaOther

Question 6

Ticarcillin/clavulanate

Answer 6

Group: PenicillinSpectrum: G+ and G- enterbacteriaceae, MSSA, E. faecalis, pseudomonas, anaerobes.Common Indications: sepsis, polymicrobial infection, intraabdominal infection, febrile neutropeniaOther

Question 7

Cephalexin PO

Answer 7

Group: CephalosporinSpectrum: MSSA, B-hemolytic Strep.Common Indications: SSTIOther: 1st gen

Question 8

Cefazolin IV

Answer 8

Group: CephalosporinsSpectrum: MSSA, Strep., E. coli, Proteus, KlebsiellaCommon Indications: SSTI, bone/joint infection, surgical prophylaxisOther: 1st gen

Question 9

Cefuroxime IVCefuroxime axetil POCefprozil PO

Answer 9

Group: CephalosporinsSpectrum: S. pneumoniae, H. influenzae, M. cattarhalisCommon Indications: 2nd line for community acquired respiratpry infectionsOther: 2nd generation

Question 10

Cefotaxime IV

Answer 10

Group: CephalosporinsSpectrum: Streptococci, G- enterobacteriaceae, H. influenza, M. cattarhalisCommon Indications:SSTI, urosepsis, endocarditis, meningitisOther: no pseudomonas activity, 3rd gen

Question 11

Ceftriazone IV

Answer 11

Group: CephalosporinSpectrum: Streptococci, G- enterobacteriaceae, H. influenza, M. cattarhalis, N. gonorrheaeCommon Indications:urosepsis, gonorrhea, endoccarditis, SSTI, meningitisOther: 3rd gen

Question 12

Cefixime PO

Answer 12

Group: CephalosporinSpectrum: streptococci, G- enterobacteriaceae, H. influenzae, M. cattarhalis, N. gonorrheaeCommon Indications: UTI, gonorrheaOther: 3rd gen

Question 13

Ceftazidime IV

Answer 13

Group: CephalosporinSpectrum: Pseudomonas aeruginosaCommon Indications: in combination with aminoglycosides for severe Pseudomonas infectionOther: 3rd line, no G+ activity

Question 14

Cefepime IV

Answer 14

Group: CephalosporinSpectrum: G+, S. pneumoniae, MSSA, G- enterobacteriaceae, P. aeruginosaCommon Indications: in combination with aminoglycosides for severe Pseudonmonas infection, febrile neutropenia, polymicrobial infectionOther: 4th gen

Question 15

Ertapenem IV

Answer 15

Group: CarbapenemsSpectrum: G+, MSSA, G- enterobacteriaceae, ESBL/AmpC producers, anaerobesCommon Indications: Outpatient Rx of polymicrobial infections or MDR organismOther: no pseudomonas, entercoccus activity

Question 16

Meropenem IV

Answer 16

Group: carbapenemSpectrum: G+, MSSA, G- enterobacteriaceae, ESBL/AmpC producers, anaerobes, pseudomonasCommon Indications: trauma/surgical meningitis, polymicrobial infection with suspected MDROther: no enterococcus activity

Question 17

Imipenem IV

Answer 17

Group: CarbapenemSpectrum: G+, MSSA, G- enterobacteriaceae, ESBL/AmpC producers, anaerobes, pseudomonas, E. faecalisCommon Indications: polymicrobial infections with suspected MDR. NEVER for community acquired infection