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IDMM > Is the drug class bactericidal or bacteriostatic (+MOA)? > Flashcards

Is the drug class bactericidal or bacteriostatic (+MOA)? Flashcards

1
Q

Glycopeptides

A

Bactericidal- cell wall synthesis inhibition

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2
Q

Lipopeptides

A

Bactericidal- disruption of cell wall membrane

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3
Q

Aminoglycosides

A

Bactericidal- binds to 30S subunit

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4
Q

Macrolides

A

Bacteriostatic- binds to 50S subunit

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5
Q

Lincosamides

A

Bacteriostatic- binds to 50S subunit

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6
Q

Tetracyclines

A

Bacteriostatic- binds to 30S (and 50S?)

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7
Q

Glycylcyclines

A

Bacteriostatic- binds to 30S (and 50S?)

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8
Q

Fluroquinolones

A

Bactericidal- inhibit DNA gyrase and topoisomerase

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9
Q

Anti-folates

A

Bacteriostatic (Nitrofurantoin bactericidal but only achieves therapeutic concentration in urine)- inhibit enzymes in folate pathway

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10
Q

Nitroimidazoles

A

Bactericidal- inhibit DNA synthesis

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11
Q

Oxazolidinones

A

Bacteriostatic- binds to 50S

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12
Q

Rifampin

A

Bactericidal- binds RNA pol

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13
Q

Isoniazid

A

Bactericidal- inhibits mycolic acid synthesis

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14
Q

Pyrazinamide

A

Bactericidal- inhibits mycolic acid synthesis

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15
Q

Ethambutol

A

Bactericidal- inhibits polymerization of arabinoglycan in mycobacterial wall

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16
Q

Penicillins

A

Bactericidal- cell wall synthesis inhibitor

17
Q

Carbapenems

A

Bactericidal- cell wall synthesis inhibitor

18
Q

Cephalosporins

A

Bactericidal- cell wall synthesis inhibitor

IDMM (33 decks)

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