mixed review deck 8 Flashcards
What is a teratogen?
Anything introduced during pregnancy that impacts the typical development of a fetus
4 categories of teratogenic effects
carcinogenic, lethal, malformations, and cerebral effects
What is the approximate threshold dose for all of these types of teratogenic effects: lethal effects, malformations, and cerebral effects?
about 100 mGy
During what stage of pregnancy are lethal effects most likely?
pre-implantation (at a threshold of 100 mGy)
What general category of teratogenic effects are most likely to occur during organogenesis (10 days to 6 weeks)
malformations (including growth retardation, microcephaly–obvious physical deformities)
During the fetal period (6 weeks to birth), what category of teratogenic effects are most likely to occur?
cerebral effects (microcephaly, mental retardation, reduced IQ)
What is the average FETAL dose of an AP abdomen x-ray?
3 mGy
Average dose to the fetus for an AP L-spine
4 mGy
Average fetal dose for an IVU
8 mGy
Average dose to the fetus for a CT abdomen exam and a CT pelvic exam
CT abdomen, 10 mGy
CT pelvis, 20 mGy
4 fluoroscopic procedures with fetal doses that approach the 100 mGy threshold for teratogenic effects
barium enema (17 mGy)
hysterosalpingogram (30 mGy)
UGI with small bowel series (40 mGy)
cystourethrogram (50 mGy)
Acute radiation syndrome is a ____ effect with a ____ threshold that occurs ____ after exposure.
deterministic effect, very high threshold, occurs soon after exposure (early effect)
Define LD 50/60
the dose of radiation that will kill 50% of the population within 60 days with no medical intervention
What is the LD 50/60 for humans?
Between 3-4 grey
x-ray tube rating is calculated and expressed as …
the allowable kilowatts (kW) per 0.1 seconds
tube loading refers to …
the heat created within the x-ray tube
Name the 4 main factors influencing tube loading
exposure time, filament size, anode angle, anode rotation speed