Mitotic Cell division Flashcards

1
Q

Packing benefits?

A
  • Reduced the length (shortens it)
  • reduces the rate of mutation
    *enables more precise gene expression
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2
Q

How many nuclear molecules are there? What to they interact with?

A

There are 46 nuclear molecules that interact with his tone proteins

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3
Q

The DNA contains——— DNA molecules in the form of chromatin?

A

92

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4
Q

During mitosis what happens?

A

The spindle separates each pair of the sister chromatids to ensure that each cell inherits 46 molecules

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5
Q

The Spindle does what to the chromosomes?

A

Coordinates the movement of the chromosomes during mitosis

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6
Q

The Spindle is formed by?

A

Protein filaments called micro molecules

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7
Q

Each Micromolecule is formed from?

A

Polymerization of Tublin Proteins

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8
Q

The Spindle mircotubles attach to a what?

A

Structure on each sister chromatid called kinechore

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9
Q

Motor proteins enable what?

A

Each sister chromatid to move along the spindle’s microtubules

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10
Q

Mitotic cell division enables what?

A

All eukaryotic cells to reproduce

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11
Q

Single cell eukaryotes use mitotic cell division to—

A
  • Reproduce asexually
  • purge toxins & defective organelles
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12
Q

Mitotic cell division is essential for what?

A

All multi cell eukaryotes

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13
Q

Mitotic cell division supplied the new cells that enable your body to——

A
  • Grow
  • Repair
  • Renew (replace)
  • Produce Hair
  • Defend Itself (Immune System)
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14
Q

Mitotic Cell division occurs during—-

A

The Mitotic (M)Phase of the Cell Cycle

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15
Q

What does the M phase generate?

A

It generates two, independent,” Daughter Cells”

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16
Q

What are in two independent daughter cells?

A
  • 46 chromosomes (chromatin molecules) in the nucleus
  • A complete set of organelles
  • The exact size required to perform their bodily functions
17
Q

Mitotic Cell Division has 2 major processes called?

A

Mitosis and Cytokinesis

18
Q

Mitosis has how many nuclei in the adult stem cell?

19
Q

What do the 2 nuclei ensure?

A

That each daughter cell inherits a nucleus with 46 chromosomes

20
Q

After mitosis, the adult stem cell briefly has 2 what?

A

Nuclei that contain 46 Chromosomes

21
Q

Mitosis enables the cell to?

A

“Duplicate The Nucleus”

22
Q

How many stages are there?

A

5 (Prophase,Prometaphase,Metaphase,Anaphase,Telophase)

23
Q

Prophase

A

Is the first of the five stages

24
Q

Prophase (description)

A

Chromatin molecules condensed into shorter chromosome.

#spindle becomes functional.
#Large organelles (nuclear envelope, Golgi apparatus ER) Cytoskeleton disassemble

25
Prometaphase
Second stage
26
Prometaphase (description)
*The Kinetochore forms at the centromere of each sister chromatid. * spindle microtubules attach to the kinetochore. * The spindle move all 46 pairs of Sister chromatids towards the cell center
27
Metaphase
Is the third stage of Mitosis
28
Metaphase (Description)
* The Spindle Positions All 46 Pairs Of Sister Chromatids At The Cell’s Center (Equator) To Form The Metaphase Plate *Each Sister Chromatid Of A Pair Is Attached To A Different Half Of The Spindle To Ensure That 46 Chromosomes Are Delivered To Each End Of The Cell *The Mitotic Phase (Spindle) Checkpoint Verifies The Attachment Of The Spindle Microtubules To The Kinetochore Of Each Sister Chromatid
29
Anaphase
Is the 4th stage
30
Anaphase(description)
Anaphase A & Anaphase B Ensure That 46 Chromosomes Are Delivered To Opposite Ends Of The Adult Stem Cell *During Anaphase A, The Motor Proteins In The Kinetochore Pull Each Chromosome Toward One End Of The Cell *During Anaphase B, The Two Halves Of The Spindle Move Apart As The Microtubules Of Each Half Push Past One Another
31
Telophase
Is the 5th and final stage
32
Telophase (Description)
●Each Chromosome Unwinds Into Its Longer Chromatin Form ●Nuclear Envelope Reforms Around The 46 Chromatin Molecules At Opposite Ends Of The Cell To Form Two Nuclei ●Golgi Apparatus & ER Reform ●Spindle Disassembles & Tubulin Proteins Will Rebuild The Cytoskeleton ●After Telophase Is Accurately Completed, The Cell Separates Into Two, Independent, Daughter Cells During Cytokinesis
33
The Process Of Cytokinesis Begins After—-
Mitosis Is Complete The Cell Physically Separates To Produce Two Daughter Cells
34
The Actin-Myosin II- ———
Contractile Ring Forms On The Inner Surface Of The Cell Membrane To Perform The Cell Separation (Cleavage) Process
35
M Phase (Spindle) Checkpoint Failure Consequences
●Defective Checkpoint Sensors Prevent The Spindle From Separating One Or More Pairs Of Sister Chromatids (“Nondisjunction”) *Nondisjunction Causes Aneuploidy [Abnormal Chromosome Number (2n ≠ 46) In The Nucleus] *Many Aneuploid Human Cells Self-Destruct By Apoptosis *Aneuploid Cells Suppress The Immune System, Increase The Risk Of Cancer, And Increase The Rate Of Aging