Miscellaneous Flashcards

1
Q

Echinacea modulates the immune system by several mechanisms.

A

Increases phagocytosis, IL1,6,10 TNF-alpha.

Has anti-inflammatory actions and antimicrobial actions.

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2
Q

Echinacea is used in treatment of common cold and has flu-like syndrome as a side effect. Yes or No?

A

Yes.

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3
Q

Garlic has antihypertensive properties and antidyslipidemic as well.

A

It inhibits ACE and has antioxidant effect and also decreases the enzyme HMG-coA reductase which decreases cholesterol.

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4
Q

What are the uses of Gingko Biloba?

A

Memory enhancement in Alzheimer’s and dementia, in intermittent claudication.

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5
Q

Mention two substances that have antineoplastic properties.

A

Garlic and St. John’s Wort

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6
Q

What’s the use of Saw Palmetto?

A

In BPH as it reduces the enzyme 5alpha reductase and prostatic growth factor

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7
Q

What is the substance that’s used in statin induced myopathy?

A

Coenzyme Q10

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8
Q

What does deficiency of vit. B1 cause?

A

Beri beri

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9
Q

What does the deficiency of vit. B2 cause?

A

Stomatitis, glossitis, dermatitis, anemia and neuropathy.

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10
Q

What’s the enzyme that’s used in treatment of isoniazid peripheral neuropathy and vomiting in pregnancy?
And what’s the outcome of its deficiency?

A

Vit. B6

Its deficiency causes dermatitis, anemia and peripheral neuritis.

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11
Q

What’s the outcome of vit. B3 deficiency?

A

Pellagra (diarrhea, dermatitis, dementia)

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12
Q

What’s the vitamin deficiency that causes neuromuscular degeneration and adrenocortical insufficiency?

A

Pantothenic acid.

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13
Q

What vitamin is used in treatment of acne? And what’s the outcome of its deficiency?

A

Vit. A (Isoretinoin)

Its deficiency causes night blindness, dry skin and urinary calculi.

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14
Q

What’s a vitamin that’s teratogenic?

A

Vit. A

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15
Q

What does vit. E deficiency cause?

A

CNS degeneration, muscle atrophy and atherosclerosis.

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16
Q

Dimercaprol is used for chelating which heavy metals? Hint: MAGA

A

Mercury, Arsenic, Gold, Antimony

17
Q

Dicobalt edetate is used in chelation of which heavy metal?

A

Cyanide.

18
Q

Disodium edetate is used in chelation of?

A

Calcium

19
Q

Deferoxamine is used to chelate what? And what other substance is used to chelate the same heavy metal?

A

IV for iron

Deferasirox and Deferipone are used orally to chelate iron as well.

20
Q

D-penicillamine is used in chelation of? Hint: CML

A

Copper in Wilson’s disease

Mercury and Lead

21
Q

Trientine is used in chelation of?

A

Copper

22
Q

Succimer is used in chelation of? Hint:MAL

A

Mercury, Arsenic and Lead

23
Q

Calcium lactate used as a diluent may chelate what?

A

Tetracycline

24
Q

Ampicillin, ascorbic acid and barbiturates react with what?

A

Dextran solutions

25
Q

Benzyl penicillin, erythromycin and gentamicin, and hydrocortisone react with what?

A

Heparin solutions.

26
Q

Never mix thiopental with?

A

Succinylcholine

27
Q

PZI + soluble insulin cause precipitation of what?

A

Soluble insulin

28
Q

What PNS decreases the effect of warfarin?

A

Coenzyme Q10

29
Q

What PNS causes cross allergy with people with shellfish allergy?

A

Glucosamine

30
Q

What PNS causes infertility and why?

A

Melatonin

Due to inhibition of LH and sperm formation

31
Q

What botanical substance is used in treatment of hypertension and atherosclerosis?

A

Garlic

32
Q

What botanical substance is used to prevent GI cancer?

A

Garlic

33
Q

What substance is used in treatment of Alzheimer’s disease and dementia?

A

Gingko biloba

34
Q

Ginseng is used to decrease postprandial glucose. Why?

A

It increases insulin release and sensitivity

35
Q

What’s the botanical substance used in treatment of sciatica?

A

St. John’s Wort

36
Q

Ginseng causes estrogenic side effects.

A

Mastalgia and vaginal bleeding.