Miscellaneous Flashcards

1
Q

Define broad spectrum in relation to antibiotics

A

Covers gram positives and negatives

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2
Q

Name drugs used in malaria treatment ?

A

Chloroquine

Chlorquine resistant regions:
Quinine + doxycycline
Or
Artesunate

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3
Q

List Signs of severe C diff infection?

A

Fever
AKI
Abfo pain and distension;
Toxic megacolon

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4
Q

Which organism is not killed by alcohol gel so requires hand washing

A

C diff

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5
Q

Which abx are particularly implicated in c diff infection?

A

1.Clindamycin
Co-amixiclav
Ciprofloxacin
Broad spectrum Abx in general

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6
Q

GUM

what is the treatment for thrush?

A

co-trimoxazole / canesten

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7
Q

GUM

what is the treatment for chlamydia?

A

doxycycline

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8
Q

GUM

what is the treatment for Gonorrhea?

A

Ceftriaxone

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9
Q

GUM

what is the treatment for BV?

A

Metronidazole

Dalacin cream

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10
Q

rifampicin will enhance metabolism of which of these drugs?

prednisolone 
losartan
rampril
perindopril
amiodarone
A

prednisolone

Rifampicin accelerates the metabolism of corticosteroids and causes a reduced effect.

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11
Q

go and do capsule infection medicine and therapeutics questions!

A

https://learn.capsule.ac.uk/cases/168

lots of overlap and stuff not covered here!

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12
Q

list 3 main differentials for a maculopapular rash an lymph nodes ?

A
  1. Acute HIV
  2. Secondary syphilis (lymph nodes present in primary syphilis too)

3, infectious mononucleosis

meningitis does not involve lymph nodes

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13
Q

what counts as a neutropenia?

A

neutrophil count less than 1

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14
Q

why is spinal cord compression an oncological emergency?

A

fast growing tumour can lead to bladder and anal sphincter function loss ;

patient loses their dignity
-also lower limb weakness

can prevent but cant reverse so acting fast is important

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15
Q

how to treat spinal cord compression?

A

drxamethasone - reduces inflammatoin and cordal compression

refer to neuro team

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16
Q

rx for neutropaenic sepsis?

A

adjuvant chemotherapy - important

Granulocyte colony stimulating factor

17
Q

list the oncological emergencies?

A
  1. Neutropenic sepsis
  2. Metastatic spinal cord compression
  3. Superior vena caval obstruction
  4. Hypercalcaemia
  5. Tumour lysis syndrome