Global health priorities and brain worms Flashcards

1
Q

according to the 2016 WHO list, what the the top 10 most common causes of mortality in the world?

A
  1. IHD
  2. Stroke
  3. COPD
  4. LRTI
  5. Alzheimers + dementia
  6. Respiratory cancers
  7. Diabetes
  8. Road injury
  9. Diarrhoea
  10. TB
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2
Q

what is a DALY?

A

measures morbidity and mortality caused by a condition as 1 metric

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3
Q

rank the following in terms of DALY score. 1 being highest and 5 being lowest:

LRI
IHD
NN preterm
Back pain
Stroke
A
IHD
Stroke
LRI
Back pain
NN preterm
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4
Q

how does one assess the value of a medical intervention?

A

QALY

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5
Q

A year in the hypothetical state of “perfect health” is worth how many QALYs.

A

1

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6
Q

list some measurements of global health?

A

QALY
DALY

Maternal mortality
Infant mortality
Life expectancy
Human development index

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7
Q

List some causes of a solitary ring enhancing lesion on CT?

A

Most common:
Neuro-Cysticercosis
Tuberculoma

Less common:
Abscess
Toxoplasmosis
Lymphoma - PCNSL
Sarcoid

Mets

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8
Q

toxoplasmosis and cryptococcosis cause ring enhancing lesion in which individuals?

A

immunocompromised.

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9
Q

toxoplasmosis ring enhancing lesion occurs where?

A

around basal ganglia

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10
Q

what is the commonest cause of adult-onset epilepsy in many countries?

A

Taenia solium cysticercosis

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11
Q

what is the source of Taenia solium cysticercosis?

A

with pork tapeworm larvae

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12
Q

name the 2 types of INFECTION caused by Taenia solium?

A

Taeniasis - Intestinal infection with ADULT stage of large tapeworms; T. solium and T. saginata

Cysticercosis - Tissue infection with LARVAL stage of T. solium

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13
Q

which taenia causes cysticercosis?

A

T. solium

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14
Q

which taenia causes intestinal infection?

A

T. solium and T. saginata

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15
Q

if you get pig tapeworm, will you get cysticercosis?

A

No.

you will poop out tapeworm eggs, then people can get infection from its larva.

the tapeworm doesn’t want to kill you because it relies on you to live.

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16
Q

symptoms of Taeniasis?

A

asymptomatic usually

17
Q

mechanism of Porcine cysticercosis?

A

this is when pigs get cysticercosis

pigs eat human poop so ingest tapeworm eggs in human faeces

parasites migrate to tissues & encyst -> measly pork

18
Q

how does one get tapeworm from pig

A

eat undercooked or raw pork

19
Q

rate the likelihood of getting cysticercosis:

  1. Carnivore
  2. vegetarian
  3. Vegan
  4. Muslim
  5. Jew
A

Can all get cysticercosis because cysts spread through faces contaminated food.

only carnivores can get the tapeworm though

20
Q

what is the cause of symptomatic disease here?

A

brain cysticerci

21
Q

symptoms of neurocysticercosis?

A

in order of likelihood:

epilepsy
raised intra-cranial pressure
headache
altered mental state

22
Q

treatment for neurocysticercosis?

A

anticonvulsant - epilepsy

ventriculo-peritoneal shunt - hydrocephalus

Albendazole/praziquantel

steroids - suppress inflammatory response of treatment