Miscellaneous

Question 1

Main reservoir for magnesium

Answer 1

Intracellular in bone/muscles

Question 2

Main absorption site magnesium

Answer 2

Small intestine by passive paracellular diffusion

Question 3

Main site of renal magnesium reabsorption

Answer 3

TALOH

Question 4

Main effect of magnesium on muscle

Answer 4

Calcium uptake by sarcoplasmic reticulum

Question 5

CKD effect on magnesium

Answer 5

Usually high

Question 6

3 meds causing magnesium wasting

Answer 6

Aminoglycosides
CNIs
Cisplatin

Question 7

Best Rx chronic insomnia

Answer 7

CBT

Question 8

Varenicline or bupropion for smoking cessation, which is better?

Answer 8

Vareniclin

Question 9

Fasted component of Wernicke’s to resolve with thiamine replacement

Answer 9

Occular palsies

Question 10

Fabry’s diease is deficiency of:

Answer 10

Alpha-galactosidase A

Question 11

Mode of inheritance Fabry’s

Answer 11

XLR

Question 12

In Fabry’s, what accumulates in tissues:

Answer 12

Glycosphingolipid

Question 13

Manifestations of Fabry’s

Answer 13

Neuropathy, renal failure, cerebrovasc disease, angiokeratomas

Question 14

Rx Fabry’s

Answer 14

Alpha-gal A enzyme replacement

Question 15

ECG findings in hypothermia

Answer 15

J-waves (Osborne waves)

Others - absent P waves, prolonged PR/QRS/QT

Question 16

Best opioids in renal failure:

Answer 16

Fentanyl, bup, methadone

Question 17

Best opioids in liver failure

Answer 17

None, avoid if possible

Question 18

Max dose Targin before switch to oxycontin

Answer 18

40/20 BD

Question 19

Receptors for vestibular mediated nausea

Answer 19

ACh, H1

Question 20

CTZ nausea receptors

Answer 20

5HT3, D2

Question 21

Vagal afferent receptors for nausea from distention:

Answer 21

5HT3/4, D2