Dermatology Flashcards

1
Q

Which bacteria causes nail infections?

A

Pseudomonas

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2
Q

Yellow nail syndrome triad

A

Nail changes, lymphoedema, resp (pleural eff, bronchitis)

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3
Q

Yellow nail syndrome associations

A

RA, malignancy, immunodeficiency

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4
Q

Yellow nail syndrome Rx

A

Vit E, zinc, itraconazole

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5
Q

Granuloma annulare associations

A

T2DM, thyroid disease, lymphoma, HIV

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6
Q

Granuloma annulare mechanism

A

Delayed hypersensitivity for components of dermis, driven by TNFalpha

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7
Q

Proportion of sarcoidosis that get skin involvement

A

1/3

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8
Q

Derm manifestations of sarcoidosis

A

Plaque, mac-pap eruptions, erythema nodosum, erythema multiforme

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9
Q

Local Rx sarcoid skin disease

A

Topical steroids

If severe - MTX

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10
Q

Most common presentation of cutaneous T-cell lymphoma

A

Mycosis fungoides

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11
Q

Management options cutaneous T-cell lymphoma

A

Avoid antigen, UVB, MTX, extracorporeal photopheresis

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12
Q

3 causes of Sweet’s

A

AML, pregnancy, RA, IBD, drugs

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13
Q

Rx of Sweet’s

A

Withdraw cause, steroids

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14
Q

Where does pyoderma occur

A

At site of minor trauma

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15
Q

Key complication of pyoderma

A

Deep fungal infection e.g. scedosporidium

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16
Q

Vitiligo - when repigmentation occurs, where does it occur?

A

Follicles

17
Q

What is Koebner’s phenomenon?

A

Vitiligo worse at sites of scars

18
Q

Rx vitiligo

A

Steroids, CNIs, UVB

19
Q

Erythema multiforme description

A

Bilateral fixed papules +/- target lesions

20
Q

Triggers for erythema multiforme

A

Mycoplasma, EBV, CMV, HSV, HIV, hepatitis

21
Q

DIfference between major and minor erythema multiforme

A

Mucosal involvement

22
Q

Cut-off SJS vs TEN

A

TEN >10% epidermal detachment, SJS <10%

23
Q

Nikolsky sign SJS/TEN

A

Epidermal detachment with gentle pressure

24
Q

Main part of body affected SJS/TEN

A

Trunk

25
Q

Key specific Rx SJS/TEN beyond supportive

A

IVIg 1g/kg/d for 3/7

26
Q

What UV are we mostly exposed to?

A

UVA 95%

27
Q

Which UV penetrates deeply

A

UVA

28
Q

Which UV is sunscreen based upon

A

UVB

29
Q

Actinic keratoses are precursors to:

A

SCC

30
Q

Which haem malignancy gets very aggressive SCC

A

CLL

31
Q

Describe dermatitis herpetiformis

A

Itchy vesicular lesions found on extensor surfaces, back, scalp

32
Q

Dermatitis herpetiformis assocxiation

A

Coeliac

33
Q

Porphyria cutanea tarda is due to deficiency in:

A

UROD

34
Q

Porphyria cutanea tarda associations

A

Alcohol excess
Hep B/C
Iron overload

35
Q

Diagnosis of porphyria cutanea tarda

A

Elevated urine or plasma porphyrins

36
Q

Erythema nodosum causes

A

Sarcoid, IBD, OCP, pregnancy, cancer, infection

37
Q

Which infection is EN associated with?

A

Strep pharyngitis

38
Q

Treatment of erythema nodosum

A

NSAIDs

39
Q

Bullous pemphigoid description

A

Tense subepidermal blisters