MISC - Cholinergic and Adrenergic Receptors Flashcards
Contraction of most smooth muscles (Adrenoreceptor type)
α1
Dilation of pupils (Adrenoreceptor type)
α1
Erection of hair/Goosebumps (Adrenoreceptor type)
α1
Contraction of prostate (Adrenoreceptor type)
α1
Inotropic effect (Increased force of contraction in heart) (Adrenoreceptor type)
α1
Aggregation of platelets (Adrenoreceptor type)
α2
Inhibition of transmitter release (Adrenoreceptor type)
α2
Contraction of some smooth muscles (Adrenoreceptor type)
α2
Inhibition of lipolysis (breakdown of fats) (Adrenoreceptor type)
α2
Increased force and rate of contraction in heart and juxtaglomerular cells (Adrenoreceptor type)
β1
Increased renin release (Adrenoreceptor type)
β1
Promotes smooth muscle relaxation of the respiratory, uterine, and vascular smooth muscles (Adrenoreceptor type)
β2
Promotes potassium uptake in the skeletal muscle (Adrenoreceptor type)
β2
Activates glycogenolysis in the liver (Adrenoreceptor type)
β2
Relaxes the detrusor muscle in the bladder (Adrenoreceptor type)
β3
Activates lipolysis (breakdown of fats) (Adrenoreceptor type)
β3
Dilation of renal blood vessels (Adrenoreceptor type)
D1
Modulate transmitter release in nerve endings (Adrenoreceptor type)
D2
Positive inotropic and chronotropic effect is via the __________ receptor (Adrenoreceptor type)
β1
Vasoconstriction in most blood vessels is via the __________ receptor (Adrenoreceptor type)
α1
Vasodilation in some blood vessels is via the __________ receptor (Adrenoreceptor type)
β2
Bronchodilation is via the __________ receptor (Adrenoreceptor type)
β2
Inhibition of insulin secretion is via the __________ receptor (Adrenoreceptor type)
α2
Promotion of insulin secretion is via the __________ receptor (Adrenoreceptor type)
β2
Promotion of glucagon secretion is via the __________ receptor (Adrenoreceptor type)
β2
Glycogenolysis is via the __________ and __________ receptor (Adrenoreceptor type)
α1, β2
Lipolysis is via the __________ receptor (Adrenoreceptor type)
β3
Alzheimer’s disease, Cognitive dysfunction, Schizophrenia (Cholinergic receptor type)
M1
Alzheimer’s disease, Cognitive dysfunction, Pain (Cholinergic receptor type)
M2
COPD, Urinary incontinence, IBD (Cholinergic receptor type)
M3
Parkinson’s disease, Schizophrenia, Neuropathic pain (Cholinergic receptor type)
M4
Drug dependence, Parkinson’s disease, Schizophrenia (Cholinergic receptor type)
M5
Miosis (pupil contraction) is via the __________ receptor (Cholinergic receptor type)
M3
Sweating is via the __________ receptor (Cholinergic receptor type)
M3
Smooth muscle bronchoconstriction is via the __________ receptor (Cholinergic receptor type)
M3
Mad hatter symptom is via the __________ receptor (Cholinergic receptor type)
Nicotinic
Hypotension due to higher doses of oxymetazoline, naphazoline, and xylometazoline is via the __________ receptor
α2
Phentolamine and phenoxybenzamine decrease TPR via __________ antagonism
α1
β antagonists lead to negative inotropic and chronotropic effect via __________ antagonism
β1
β antagonists lead to decreased renin secretion by juxtaglomerular cells via __________ antagonism
β1