misc 3 Flashcards
Scala media is separated from scala vestibuli by ……
Reissner’s (vestibular) membrane
The first fetal movement occurs at …..
2 months
Cleidocranial dysostosis affects bones of ……
intermembranous ossification origin
* causes defect in skull, facial bones & clavicle. Also dental anomalies
Upper fibers of the trapezius ……., while the lower fibers ……..
elevate the acromion
depress the medial of the scapula
* Flexion of neck is through the SCM (one side of SCM will turn face sideways)
* elevation of scapula is through levator scapulae & rhomboids
The sciatic nerve controls ……
knee flexion
- It is the longest nerve in the body
- Derived from sacral plexus
- Supply all muscles of foot, leg, and posterior thigh
- In contrast, femoral N. responsible for knee extension
- Divides at the back of the knee into lateral peroneal N. & medial tibial N
The obturator nerve supplies ……..
the medial aspect of the thigh
* Hip adduction
A patient with a foot drop may indicate damage to ……..
deep peroneal (fibular) nerve
Hip abduction is mediated by …….
superior gluteal N
The origin of the cerebellar climbing fibers is ……
the medullary olivary nucleus
Conc. of RBC is higher in men due to …….
erythrogenic effect of androgen
* In men 4.5 - 6 million/mm3
Hematocrit for men is ……
40 - 55%
Sickle cell anemia is the result of …….
single base pair substitution of valine for glutamic acid at the 6th position of the b subunit of hemoglobin
* In this disease, RBCs lose their pliability, causing clogging of capillaries
G6PD deficiency leads to ………
hemolytic anemia due to decrease NADPH and inability to maintain RBC membrane
* Induced by sulfa drugs, fova beans & oxidants
After Hb break down, iron binds to ……, and then it combines with …..
transferrin
apoferritin (to form ferritin)
Neutrophiles have …. lobes and contain …..
3 - 5 lobes
azurophilic granules (lysosomes)
* Primary cells of acute inflammation
* Comprise 60%
Eosinophilia is ……..
increase in the number of eosinophils with parasitic infection, neoplasms, asthma or allergy
The largest of the peripheral blood cells is ……., which have a ….. nucleus
monocyte
kidney shaped
* Constitutes 1 - 3 %
* Nucleus stains lighter than lymphocyte due to loosely arranged chromatin
The life span of platelets is around …..
10 days
Platelets have two zones, …. & …..
hyalomere (peripheral, light staining) & granulomere (central, dark staining, with granules, mitochondria)
* no nucleus
Plasma contain the following proteins …….
albumin, globulin (alpha, beta, gamma), fibrinogen
- Plasma is in equilibrium with extracellular fluid
- Serum lacks fibrinogen
Lymph returns ……. into the circulation
escaped plasma proteins, lymphocytes & antibodies
Lymphatic capillaries begin as …….. and the endothelium ……
blind pouches or saccules
lack a continuous basal lamina
Lymph vessels are not found in …….
nervous system, cartilage, thymus
Hematopoiesis takes place in ……..
proximal ends of long bones, vertebrae, sternum, ribs, pelvis, flat bones of skull
The process of erythropoiesis is characterized by ……..
progressive decrease in size, gradual decrease in organelles, and progressive increase in Hb
Pyknosis is …….
the irreversibe condensation of the chromatin in the nucleus. Followed by karyorrhexis (fragmentation of nucleus)
The last cell to undergo mitosis in erythropoiesis is …….
the polychromatophilic erythroblast (checkerboard chromatin)
What are the stages of erythrocytes formation?
- Proerythroblast
- Basophilic erythroblast
- Polychromatic erythroblast
- Normoblast
- Reticulocyte
- Erythrocyte
The bone marrow is ……
highly sensitive to radiation, highly mitotic, and not highly specialized tissue
The last cell to undergo mitosis is granulopoiesis is …..
Myelocyte
* Also, the distinct granules for each type is included by Golgi in this stage
Bandemia is ……..
the acute increase in the number of band neutrophils. Indicates acute infection
Promonocyte differentiate from …..
monoblast. Gives rise to monocytes
* Monopoiesis is characterized by reduction in size & indentation of nucleus
The largest cell in the bone marrow is …..
megakaryocyte
* produced from megakaryoblast, which undergo mitosis
Megakaryocyte nucleus undergoes ……
nuclear division without cytoplasmic division
The spleen lies into the ……… region and is protected by ……
hypochondriac
rib cage
* Covered by peritoneum
The splenic vessels pass in the ……
lienorenal ligament
The lumbar lymph nodes drain …..
the legs, pelvis, gonads, kidneys, and hindgut
* The efferents drain through the lumbar trunks into cysterna chyli
Cysterna chyli is …..
the initial dilated portion of the thoracic duct at the level of L2
The thoracic duct passes the diaphragm through …….
the aortic orifice
Atrial septal defect develops if ……
septum primum fails to fuse with the endocardial cushion
Testlet 72 anatomy