Mini block 2 Flashcards
What is arteriosclerosis?(Look at slide 43/1)
It is a generic term applied to the thickening and the loss of elasticity of arterial walls.
What is the most important pattern of arteriosclerosis and what is it characterized by?
Atherosclerosis is the most important pattern of arteriosclerosis and is characterized by the presence of atheromas (or atheromatous (fibrofatty) plaques) within the intima and media. These plaques contain cholesterol and other lipids.
What is a possible cause of arteriosclerosis in a dog?
Hypothyroidism
Look at slide 44/1
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What is an atrial rupture commonly the result of?(Slide 45/1)
Physical trauma
Fatal rupture of the uterine artery during parturition occurs occasionally in aged mares with low serum___levels.
Copper
What can lead to rupture of the internal carotid artery in horses with guttural mycosis?(Look at slide 45/1 for more information)
Mitotic vasculitis
Where can dissecting aneurysms be found in young male racing greyhounds? What can this lead to?
Found in the coronary and renal arteries and can lead to arterial rupture.
What are the three things involved in the Virchow triad?
Abnormal blood flow, hypercoagulability, endothelial injury
Look at slide 53/1
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List the five pathological processes in order from most common to least common. (Endocrine system set 2)
– disorders of growth – degeneration/necrosis – inflammation and repair – deposits and pigmentation's – circulatory disorders
What are some signs that can lead to possible diagnosis of adrenocortical carcinoma? (5)
– Bilaterally symmetrical alopecia – Polyphagia – PU/PD – Potbelly – Stinks
What are two conditions with hyperadrenocorticism that can contribute to a dog stinking?
Urinary tract infection
What is the cause of Conns syndrome in a cat?
Hyperaldosteronism
What animal is more common to see Cushing’s disease in?
Adult or aged dogs
*rare in And other animals
What is Cushing’s disease most commonly associated with?
Functional corticotroph (ACTH secretion) pituitary adenoma *only responsible to 10 to 15% of Cushing's syndrome cases and dogs.
What are the causes of a pendulous abdomen (potbelly appearance)? (3) (referring to Cushing’s disease)
– Hepatomegaly
– muscle atrophy
– redistribution of fat (obesity)
What might be associated with hepatomegaly? (Visual appearance of liver is pale and can float)
Hepatic lipidosis or glycogen deposition
What are the effects of excess cortisol caused by Cushing’s disease?(7)
Hepatomegaly, hypertension, immunosuppression, poor wound healing, muscle atrophy, PU/PDA, epidermal and follicular atrophy. (Look at slide 20)
What is calcitonis cutis associated with?
Cushing’s disease
What type of change is nodular adrenocortical hyperplasia? A. Adenoma B. Adenocarcinoma C. Senile change D. Change of scenery E. Cushing's disease
C. Senile change
What are the 3 important things to know about corticotroph adenomas?
They are active, benign tumors that secrete ACTH.
Where are most pituitary adenomas found in the horse?
Pars intermedia
What are the signs of PPID and the horse? (6)
– failure to shed – PU/PD – polyphagia – hyperhidrosis – insulin resistance – abnormal fat deposition