Miles - Cancer Bio 1 Flashcards
Benign
Expansive, slow growth, differentiates, does NOT metastasize
Adenoma
Benign epithelial neoplasm
Lipoma
Benign mesenchymal neoplasm
Malignant
Infiltrative, fast growth, poor differentiation, metastasize
Carcinoma
90% of cancer, 80% of deaths
Malignant epithelial neoplasm
Malignancy of cells that serve protective functions
Basal Cell Carcinoma
Squamous Cell Carcinoma
Malignancy of cells that secrete substances into ducts or cavities
Adenocarcinoma
Sarcoma
Malignant mesenchymal neoplasm
Solid tumor of connective tissue (except blood)
Lymphoma/Leukemia
Malignant neoplasm of lymphoid cells
How do tumors usually start?
Hyperplastic lesion which undergoes metaplasia
Dysplastic Lesions
Abnormal structure/function
Growth Process: Hyperplasia
Hyper Genesis = proliferation of cells; growth or enlargement
Growth Process: Metaplasia
Adaptive substitution of one cell type for another (pre-malignant change, replaced by more capable tissue under stress)
Growth Process: Dysplasia
Abnormality in cell size, appearance, with or without a disorganized growth pattern (ex polyps)
Metastatic Growth
Once growth invades other tissues