MIDTERM 04 - Mutation and DNA Repair

Question 1

2 types of mutation

Answer 1

Point, Frameshift

Question 2

Is any event where there is a change in the sequence of the bases of the DNA molecule

Answer 2

Mutation

Question 3

Involves single nucleotide changes (Types of mutation)

Answer 3

Point mutation

Question 4

Involves addition or removal of two or more bases in the DNA (Types of mutation)

Answer 4

Frameshift mutation

Question 5

Examples include purine to purine substitution and pyrimidine to pyrimidine substitution (Types of point mutation)

Answer 5

Transition

Question 6

Examples include purine to pyrimidine substitution and pyrimidine to purine substitution (Types of point mutation)

Answer 6

Transversion

Question 7

Involves the addition of bases in the DNA causing a shift in the reading frame (Types of frameshift mutation)

Answer 7

Insertion

Question 8

Involves the removal of bases in the DNA causing a shift in the reading frame (Types of frameshift mutation)

Answer 8

Deletion

Question 9

2 types of mutagens

Answer 9

Physical mutagen, Chemical agents

Question 10

Examples include ionizing radiation and UV light (Types of mutagens)

Answer 10

Physical mutagen

Question 11

Examples include superoxide anion free radical, nitrosoderivatives, polyaromatic hydrocarbons, intercalating agents, and nucleotide base analogues (Types of mutagens)

Answer 11

Chemical agents

Question 12

UV light can promote __________ formation

Answer 12

Thymine dimer formation

Question 13

__________ are agents that can lead to insertion mutations

Answer 13

Intercalating agents