Microorganisms Flashcards

1
Q

What are the types of microorganisms/infections

A

Viruses
Bacteria
Fungi/yeast
Protozoa
Helminths
Prions

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2
Q

What are the ‘big three’ infections

A

TB
HIV/AIDS
Malaria

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3
Q

What is trachoma and its effects

A

Bacterial disease and causes blindness (chlamydia)

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4
Q

What is toxoplasma gondii and its effects

A

It is a Protozoa and can infect all warm-blooded vertebrates

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5
Q

What is pneumocystis pneumonia (PCP) and its effects

A

It is a fungus and is most common opportunistic infection in AIDS patients

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6
Q

Forms of transmission

A

Physical contact
Ingestion
Inhalation
Via vectors

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7
Q

what makes micro-specific microorganisms harmful

A

virulence factors

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8
Q

what makes host-specific microorganisms harmful

A

inflammation factors

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9
Q

what is the intra-host adaptation

A

the immune system ignoring microorganisms at one anatomical site but react to them at another

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10
Q

what is the inter-host adaptation

A

microorganisms that cross species barriers - may not produce disease in one host but can in another

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11
Q

what is the consequence of animals and humans sharing a common ecosystem

A

zoonoses -infections spreading from animals to humans
reverse zoonoses - infections spreading from humans to animals

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12
Q

what do CFRs depend on for their estimates

A

methods used to record deaths + strategies for diagnosing infection rates

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13
Q

what can CFRs influence

A

perceptions of risk versus hazard

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14
Q

Benefits and risks of live attenuated vaccines

A

Benefits: induce strong immunity
risks: risk due to live nature - esp for immuno-compromised individuals

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15
Q

benefits and risks of dead/subunit vaccines

A

benefits: using part of microorganism usually safer
risks: not as effective as live attenuated vaccines + require adjuvants to stimulate strong immune response

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16
Q

what is a viral vector vaccine

A

genetically engineer ‘benign’ microorganism for vaccine induced protection

17
Q

what inflammatory diseases are associated with dysregulation of the immune system

A

asthma and crohn’s disease