Microcytic Anaemia Flashcards
1
Q
causes of hypochromic microcytic anaemia
A
TAILS thalassaemia anaemia of chronic disease iron deficiency lead poisoning pyridoxine responsive anaemias congenital sideroblastic anaemia
2
Q
causes of lack of iron for erythropoiesis
A
iron deficiency
anaemia of chronic disease
3
Q
causes of problems with porphyrin synthesis
A
lead poisoning
pyridoxine responsive anaemias
4
Q
haem deficiency causes
A
iron deficiency anaemia of chronic disease lead poisoning pyridoxine responsive anaemias congenital sideroblastic anaemias
5
Q
globin deficiency causes
A
thalassaemia
6
Q
what conditions is ferritin normal in?
A
haemoglobinopathies
7
Q
what conditions is ferritin high?
A
anaemia of chronic disease
sideroblastic anaemia
8
Q
when is ferritin low?
A
iron deficiency
9
Q
management of microcytic anaemia
A
- Diet
- Ferrous fumarate, gluconate or sulphate 210mg tds. Expect iron to rise 10g/l per week.
- Ferrous edetate 5mls bd is liquid form and is only really used in the paediatric setting
- Contraception is menorrhagia related e.g. mirena coil
- Transfusions
- Tranexamic acid
10
Q
ways to improve compliance with taking iron?
A
symptom control (laxatives) IV or blood transfusions instead
11
Q
presentation
A
tiredness
SOB
pallor
angular cheilitis
