Disseminated Intravascular Coagulation (DIC) Flashcards

1
Q

what is DIC?

A

excessive and inappropriate activation of the haemostatic system (primary, secondary and fibrinolysis)

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2
Q

wha causes end organ failure in DIC?

A

microvascular thrombus formation

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3
Q

causes of DIC

A

anything that causes massive tissue damage and leads to activation

  • sepsis
  • obstetric emergencies
  • malignancy
  • hypovolvaemic shock
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4
Q

presentation of DIC

A

clotting factor consumption

  • bruising
  • purpura
  • generalised bleeding
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5
Q

management of DIC

A

treat underlying cause

replacement therapy= platelet transfusions, plasma transfusions, fibrinogen replacement

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6
Q

diagnosis of DIC

A

D-dimers

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