microbiology skin Flashcards
folliculitis
s aureus or epidermidis, find by gram positive cocci treat synthetic penicillin or vancomycin
s aureus virulence factors
staphylokinase coagulase b lactamase lipases
Scalded Skin Synrome
Staph aureus, exfoliative toxin no tight junctions on skin cells. Infants elderly immunocompromised.
impetigo or pyoderma
Most S. Aureues or Group A streptococcus, spread by contact skin to skin or object, yellow vessicles. Penicillin treated.
Group A streptococcus
Particularly S. pyogenes. M protein interferes with phagocytosis, Hyaluronic Acid protein disguises.
Necrotizing fasciitis
Strep pyogenes. Flesh eating bacteria. Extreme pain out of proportion. Treat broad spectrum antibiotic or amputation.
Strep pyogenes virulence factors.
Exotoxin A overactive immune reponse.Steptolysin kills many cells.
acne
propinobacterium acnes. Gram positive. Treat with antibiotics or accutane which prevents sebum secretion.
psuedomonas infection
Gram negative bacilus found in moist decaying environments. Adhesins toxins, polysaccharide capsule. . Infection in burn victims.Diagnose with pycocyanin
gas gangrene
black muscles and skin with bubbles. Clostridium perferingen gpositive anaerobic spore forming bacillis. Toxins lyse RBCs leukocytes, massive inflammatory response. Must be introduced into dead tissue, like massive trauma. Appearance diagnostic. Penicillin antitoxin. Remove dead tissue.
small pox
orthopox virus. treat immediate vaccination.
warts
pappilomavirus. dsDNA non enveloped.cause infected cells to divide. Spread direct contact. Observation diagnosis.
chicken pox
varicella zoster virus. DsDNA enveloped. Latent in nerve cells.
rubella
mild infection. causes death of pregnancy. Rubivirus positive single stranded RNA virus. Respiratory secretions. Serological test and vaccine is live attenuated, not for pregnant or immunocompromised.
Measles
Morrbillivirus. Rubeola. Most contagious childhood disease. Koplik spots in mouth, red lesions on neck. Subacute sleroizing panencephaltis.