microbiology skin Flashcards

1
Q

folliculitis

A

s aureus or epidermidis, find by gram positive cocci treat synthetic penicillin or vancomycin

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2
Q

s aureus virulence factors

A

staphylokinase coagulase b lactamase lipases

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3
Q

Scalded Skin Synrome

A

Staph aureus, exfoliative toxin no tight junctions on skin cells. Infants elderly immunocompromised.

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4
Q

impetigo or pyoderma

A

Most S. Aureues or Group A streptococcus, spread by contact skin to skin or object, yellow vessicles. Penicillin treated.

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5
Q

Group A streptococcus

A

Particularly S. pyogenes. M protein interferes with phagocytosis, Hyaluronic Acid protein disguises.

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6
Q

Necrotizing fasciitis

A

Strep pyogenes. Flesh eating bacteria. Extreme pain out of proportion. Treat broad spectrum antibiotic or amputation.

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7
Q

Strep pyogenes virulence factors.

A

Exotoxin A overactive immune reponse.Steptolysin kills many cells.

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8
Q

acne

A

propinobacterium acnes. Gram positive. Treat with antibiotics or accutane which prevents sebum secretion.

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9
Q

psuedomonas infection

A

Gram negative bacilus found in moist decaying environments. Adhesins toxins, polysaccharide capsule. . Infection in burn victims.Diagnose with pycocyanin

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10
Q

gas gangrene

A

black muscles and skin with bubbles. Clostridium perferingen gpositive anaerobic spore forming bacillis. Toxins lyse RBCs leukocytes, massive inflammatory response. Must be introduced into dead tissue, like massive trauma. Appearance diagnostic. Penicillin antitoxin. Remove dead tissue.

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11
Q

small pox

A

orthopox virus. treat immediate vaccination.

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12
Q

warts

A

pappilomavirus. dsDNA non enveloped.cause infected cells to divide. Spread direct contact. Observation diagnosis.

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13
Q

chicken pox

A

varicella zoster virus. DsDNA enveloped. Latent in nerve cells.

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14
Q

rubella

A

mild infection. causes death of pregnancy. Rubivirus positive single stranded RNA virus. Respiratory secretions. Serological test and vaccine is live attenuated, not for pregnant or immunocompromised.

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15
Q

Measles

A

Morrbillivirus. Rubeola. Most contagious childhood disease. Koplik spots in mouth, red lesions on neck. Subacute sleroizing panencephaltis.

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16
Q

leishmaniasis

A

parastic, cutaneous,protozoan. Transmitted by sandflies. Parasite spread by macrophages. Endemic to tropics, reduce vectors.

17
Q

scabies

A

sarcoptes scabiei. Prolonged bodily contact.

18
Q

S. aureus how cause disease?

A

transmitted direct contact, grows into hair follicles,causes fever and inflammation. Immune cells cause pus (WBCs). S. aureus transient.

19
Q

diagnose folliculitis

A

penicillin, vancomycin, gram positive cocci in pus. Wash hands.

20
Q

herpes

A

glycoproteins in envelope mediate adhesion, other proteins inactivate immune system.Spread by fusion of infected cells. Spread by mucous membranes. Latency!

21
Q

3 generas of cutaneous mycoses

A

trichophyton, microsporum, epidermophytan

22
Q

cutaneous mycoses

A

tineas (athletes foot) Ringworms. tcells actually cause damage.