Microbiology of CNS Infections: Part 3

Question 1

Naeglaria Fowleri

Answer 1

Swimmers in warm water lakes and ponds

Enter nasal cavity and pass through cribriform plate and feeds on brain

Question 2

Rabies

Answer 2

ssRNA negative

Bites from animals

Pharyngeal spasms lead to hydrophobia and salivation

Negri bodies present

Travels through nerves

Question 3

Clostridium tetani

Answer 3

Tetanospasmin binds peripheral nerve terminals and transported to CNS where it cleaves synaptobrevin 2

Spastic paralysis

Gram positive rods

Lollipop appearance

Block inhibitory transmitter release

Question 4

Clostridium botulinum

Answer 4

Gram positive endospore forming rod

Home canned fruits and vegetables

Flaccid paralysis

Blocks Ach release

Question 5

Trypanosome bruce

Answer 5

Cyclic fevers due to antigenic variation

Question 6

Taenia sodium

Answer 6

Neurocystericicosis

ingestion of eggs…eggs transform to larvae and move throughout the body

Fecal oral route

pigs