Microbiology of CNS Infections: Part 2 Flashcards

1
Q

JC Virus

A

Causes PML
Think HIV compromised
Subacute neurologic deficits
Naked and via respiratory

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2
Q

Herpes simplex virus encephalitis

A

Spread through peripheral nerves
Concern in neonates

Seizures

Damage primarily linked to medial and inferior temporal lobes

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3
Q

Cryptococcus neoformans

A

Encapsulated yeast in soil of pigeons and chickens

Has PS capsule

Entes via resp tract (could have lung symptoms) and get to CNS via hematogenous dissemination

Subacute presentation

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4
Q

Coccidiomycosis

A

Through inhalation of arthroconidia from soil and germinate into spherules which rupture

SW US

Major manifestation is pulmonary but could also have persistent headache

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5
Q

Toxo gondii encephalitis

A

Ring-enhancing lesions
Can cross placenta
will see tachyzoites or cysts upon biopsy

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