Microbiology Gram Negative Bacterial Diseases Flashcards
Gm negative have cell walls?
yes
What are our gram negative Cocci
Neisseria Meningitidis
N. Gonorrhoeae
Gram negavtive coccoid rods
H. Influenzae
Bordetella Pertussis
Oxidase positive comma shapped that crows in 42 degrees celcius
Campylobacter Jejuni
Oxidase positive that grows in alkaline media
vibrio cholerae
What are our gm - rods that are lactose fermentors
Klebsiella
E.coli
What are the gram negative rods that do not ferment lactose
Pseudomonas
Shigella
Salmonella
Proteus
What gm - rods are oxidase positive
Psudomonas
What Gm- rods are oxidase negative
Shigella
Salmonella
Proteus
What are the virulence factors of neisseria
FImbria Capsule Protease (inhibit IgA) Lipid A endotoxin Oxidase positive
What does it mean to be oxidase positive
use oxygen from ETC = aerobe
What enviornment does neisseria thrive in
CO2 rich
Neisseria meningitidis has what virulence factors
Capsule made of N-acetylneuramininic acid
LOS: lipid A
What diseases does niesseria meningitidis cause and in what demographic
Meningitis
Septicemia/death
Where can neisseria gonorrhoeae replicate
In WBC’s
What diseases does N. gonorrhoeae cause
STI
Septic Arthritis
PID
Neonatal conjunctivitis
What type of medium do you grow Neisseria on
Chocolate and Thayer-Martin
What are the main characteristics of Klebsiella pneumoniae
- It is a fast lactose fermentor
- capsule (quelling reaction) swelling
-Mostly Nosocomial
Diseases that Klebsiella causes
- UTI (hospital acquired)
- Pneumonia (diabetic, alcoholic)
Red current jelly sputum is what organism
Klebsiella
What is the main type of entero hemorrhagic E. Coli
0157:H7
What are the main pathogenicities for E. coli
Plasmids
Shiga like toxin
Type III secretion system
What syndrome can E.coli cause
Hemolytic Uremia Syndrome
What are the main characteristics of Shigella
-Nonmotile
Cell to Cell transmission
Doesnt Ferment Lactose
Urease and Oxidase negative
What are the 4 F’s and what bug are they associated with
Food, Finger, Feces, Flies
Shigella
What toxin and what disease does shigella cause
has endotoxin and
Exotoxin: Shiga toxin
Watery bloody mucuousy didysentery
What is the main characteristics of salmonella
Motile
Urease and oxidase negative
What is the main sequella of Salmonella
Typhoid fever from S. typhi
Gastroenteritis, bactermeia, peritonitis
Rose spots on abdomen, Fever, headache, diarrhea or constipation think
typhoid fever
What type of E. coli has LT (heat labile) and ST(heat stable) proteins
Enterotoxigenic (ETEC)
what are the main characteristics of preoteus
Urease Positive
Oxidase negative
Flagella make it very motile
What two diseases do proteus cause
UTI
Kidney Stones
Why does urease lead to kidney stones
takes acid and makes base (ammonia) leads to struvite stones
Main characteristics of Pseudomonads
Oxidase Positive
Produces Blue-green pigment
Grape like odor
Diseases pseudomonads cause
- Wound and burn infections
- Hot tub foliculitis
What diseases does Pseudomonas aeruginosa cause
-Pneumonia: cystic fibrosis patients and immunocompromised
Ostemyelitis: dibetetic and IV drugs
- Burn wound infections
- UTI/pylo in nursing home hospital aquired
- Endocarditits in IV drug users
What are the two types of cocobacillus
describe them
Haemophilus and bordetella
Shape between rod and cocci
Anerobic
What is the main pathogeniciy of Haemophilus Influenzae
- Capsule B= bad
- IgA protease
What diesaes does Haemophilis influenzae cause
-Meningitis
-Epiglottitis
Oneumonia
What does Haemophilis ducreyi cause
painful genitial ulcer (chanchroid)
Painful inguinal lymphadenopathy
What is the epidemiology and pathogenicity of bordetella
Inhibits ciliary action
Adhesins
Toxins
What are the toxins of bordetella
Pertussis
adenylate cyclase
dermonecrotic
tracheal
what type of culture do you grow bordetella in
regan-lowe agar
what are the three stages of whooping cough
- Catarrhal stage (non descript URI)
- Paryoxysmal stage ( non productive cough with whoop, vomiting cyanosis)
- Convalescent stage (less severe persistent cough)
