Microbiology: Cooties Flashcards
H Pylori morphology
Gram neg spirochete
H pylori complication (neoplasm)
MALT lymphoma (classic)
Also adenocarcinoma
H pylori adherence and virulence factor
BabA sabA ( entra por baba)
CagA (te cagas por enfermo)
Intestinal epithelial cells that sense bacteria
M cells
Reduction of acidity predisposes to (infection)
V. Cholera
Salmonella
Bloody diarrhea aka
dysentery
Bacteria that lays down dental plaque
Strep mutans
Charcot triad (dx and triad)
Cholangitis
1) High fever
2) Jaundice
3) RUQ pain
helminth causing cholangitis
Ascaris lumbricoides
Watery diahrreah after camping
Giardia
Flask shaped ulcerations in colon, intermittent diahrrea with occasional blood, third world n
Entamoeba histolytica
Daycare watery diahrrea
Rotavirus
Rotavirus detection
Stool ELISA
HUS in child comes after infection with
E coli O157:H7
ETEC and V Cholerae virulence factors
Heat labile toxin
cholera toxin
Heat labile toxin /cholera toxin MOA
Increase cAMP
Heat stable toxin moa
Activates cGMP
Heat stable, heat labile and cholera toxin effects
cAMP/cGMP lead to increase cholride secretion which leads to sodium and water loss
Terminal ileum organisms
C jejuni
Yersenia entercolitica
Shigelosis can lead to
Toxic megacolon
Shiga toxin made by
EHEC
Shigella
E. Coli O157H7 AKA
EHEC
EHEC aka O157:H7 grows on
Sorbitol McConkey Agar SMAC
Old rice bacteria (and which is it like)
B cereus
Presents like S. Aureus
C perfringens gets to intestine by
Spores.
Campylobacter neuro shit
Guillain-Barré syndrome
Campylobacter morphology
Small, curved gram neg rod
h pyolori produces
Urease
Splits urea into ammonia and CO2 to make base
H pylori oxidase
Positive
Therapy for H pylori
PPI
Amoxicillin
Clarithromycin
TB stains
Acid fast
Carbofuschil stain
Tb agar
Lownestein
Tb is intracellular in
macrophages
Granuloma in TB due to
Cord factor that activates macrophage
Primary tb in (lobe)
Middle lung
Reactivation which lobes
Upper
Tuberculoid leprea associated with
Strong TH1 response to tuberculin
Lepromatous leprea immune response
Th2 humoral
Th1 vs Th2 leprosy treatment
Th1: dapsone, rifampin
Th2: dapsone, rifampin, clofazimine
Mycobacterium avium affects who
COPDers usually… from dust and grain
Cat scratch fever bacteria
Bartonella henselae
Bartonella morphology
Gram neg
Bacillary angiomatosis symptoms
Fever, lymph nodes, red vascular lesions
Bartonella treament
Doxycycline, macrolide
Chlamydia morphology
Gram inditerminate, intracellular, small, NO MURAMIC acid
Chlamydia stain
Giemsa
Chlamidia test
NAAT
Chlamydia trachomatis serotypes
A-C: I cant see
D-K (dick): STI
L1-L3: LGV (Lymph
Chlamydia pneumonia in infant cough
“stochato” aka short burst
Trachoma blindness from
Chlamdia A-C
Chlamydia complications
PID
Reiter syndrome
Reiter syndrome
Chlamydia affecting eyes genitals and joints
Cant see, cant pee, cant climb a tree
Chamydophila psittaci signs and spread
Spread by birds
Fevers, chills, pneumonia
Why is ricketsia intracellulrar
Cant make Coa
Cant make NAD+
Ricketsia morph
Weak gram neg coccobacillus
Rickettsia test
Weil-felix
Tests for agglutination
Ricketsia sx
Headache, fever, vasculitis
Ricketsia treatment
Doxycycline
Ricketsia prowaseki rash progression
From trunk to extremities
Spares hands feet head
Ricketsia prowaseki spread via
Louse
Ricketsia prowaseki is cause of
Epidemic typhus
Ricketsia prowaseki symptoms
Rash, Myalgia, arthralgia, encephalitis, pneumonia
Rickettsia rickettsii disease
Rocky mountain spotted fever
Rickettsia rickettsii transmission
Dermacentor tick
Rocky mountain fever rash spread
From extremities inward
Rocky mountain spotted fever symptoms
Inward rash
Myalgia
Arthralgia
Influenza virus morphology
SS RNA negative sense virus , has capsid
Influenza requires
Reverse RNA polymeraze
Where does influenza replicate
Neclues
How many segments in influenza virus
8
Antigenic variation in flu due to
Segments remixing
Influenza virulence factors
HA hemagluttinin: gets in
Neuromaninidase: Gets out
M2 protein in virus does
Modulates pH
Flu vaccines types
Nasal is live
IM is dead
Influenza pneumonia characteristic
co-infection with S. Auerus or other bugs
Malassezia furfur prep and appearance
KOH prep
Spaghetti and meatball appearance
Malassezia furfur causes
Hypo/Hyper pigmented patches with no other symptoms
Malassezia furfur layer
Most superficial
Stratum corneum
Malassezia furfur seen in which neonates
Those that get TPN
Malassezia furfur treat with
selenium sulfide
Tinea aka
Ringworm
Woods lamp diagnoses
Microsporum
How is nail fungus treated
Griseofulvin
Sporothrix schenkii morph
Dimorphic fungus
Yeast looks like cigar
Sporothrix schenkii spread along body
Ascending lymphatic
Sporothrix schenkii biopsy
Histocyte
Giant cells
cigar shaped yeast
Sporothrix schenkii treatment
Itraconazole
Fungus causing verrucous lesions
Madurella mycetomatis
Organisms that cause tinea
Dermatophytes
Microsporum
Truchophyton
Epidemophyton