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PBL 2.2.4 > Microbiology: Cooties > Flashcards

Microbiology: Cooties Flashcards

1
Q

H Pylori morphology

A

Gram neg spirochete

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2
Q

H pylori complication (neoplasm)

A

MALT lymphoma (classic)

Also adenocarcinoma

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3
Q

H pylori adherence and virulence factor

A

BabA sabA ( entra por baba)

CagA (te cagas por enfermo)

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4
Q

Intestinal epithelial cells that sense bacteria

A

M cells

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5
Q

Reduction of acidity predisposes to (infection)

A

V. Cholera

Salmonella

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6
Q

Bloody diarrhea aka

A

dysentery

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7
Q

Bacteria that lays down dental plaque

A

Strep mutans

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8
Q

Charcot triad (dx and triad)

A

Cholangitis

1) High fever
2) Jaundice
3) RUQ pain

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9
Q

helminth causing cholangitis

A

Ascaris lumbricoides

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10
Q

Watery diahrreah after camping

A

Giardia

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11
Q

Flask shaped ulcerations in colon, intermittent diahrrea with occasional blood, third world n

A

Entamoeba histolytica

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12
Q

Daycare watery diahrrea

A

Rotavirus

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13
Q

Rotavirus detection

A

Stool ELISA

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14
Q

HUS in child comes after infection with

A

E coli O157:H7

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15
Q

ETEC and V Cholerae virulence factors

A

Heat labile toxin

cholera toxin

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16
Q

Heat labile toxin /cholera toxin MOA

A

Increase cAMP

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17
Q

Heat stable toxin moa

A

Activates cGMP

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18
Q

Heat stable, heat labile and cholera toxin effects

A

cAMP/cGMP lead to increase cholride secretion which leads to sodium and water loss

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19
Q

Terminal ileum organisms

A

C jejuni

Yersenia entercolitica

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20
Q

Shigelosis can lead to

A

Toxic megacolon

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21
Q

Shiga toxin made by

A

EHEC

Shigella

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22
Q

E. Coli O157H7 AKA

A

EHEC

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23
Q

EHEC aka O157:H7 grows on

A

Sorbitol McConkey Agar SMAC

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24
Q

Old rice bacteria (and which is it like)

A

B cereus

Presents like S. Aureus

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25
Q

C perfringens gets to intestine by

A

Spores.

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26
Q

Campylobacter neuro shit

A

Guillain-Barré syndrome

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27
Q

Campylobacter morphology

A

Small, curved gram neg rod

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28
Q

h pyolori produces

A

Urease

Splits urea into ammonia and CO2 to make base

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29
Q

H pylori oxidase

A

Positive

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30
Q

Therapy for H pylori

A

PPI

Amoxicillin

Clarithromycin

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31
Q

TB stains

A

Acid fast

Carbofuschil stain

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32
Q

Tb agar

A

Lownestein

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33
Q

Tb is intracellular in

A

macrophages

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34
Q

Granuloma in TB due to

A

Cord factor that activates macrophage

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35
Q

Primary tb in (lobe)

A

Middle lung

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36
Q

Reactivation which lobes

A

Upper

37
Q

Tuberculoid leprea associated with

A

Strong TH1 response to tuberculin

38
Q

Lepromatous leprea immune response

A

Th2 humoral

39
Q

Th1 vs Th2 leprosy treatment

A

Th1: dapsone, rifampin

Th2: dapsone, rifampin, clofazimine

40
Q

Mycobacterium avium affects who

A

COPDers usually… from dust and grain

41
Q

Cat scratch fever bacteria

A

Bartonella henselae

42
Q

Bartonella morphology

A

Gram neg

43
Q

Bacillary angiomatosis symptoms

A

Fever, lymph nodes, red vascular lesions

44
Q

Bartonella treament

A

Doxycycline, macrolide

45
Q

Chlamydia morphology

A

Gram inditerminate, intracellular, small, NO MURAMIC acid

46
Q

Chlamydia stain

A

Giemsa

47
Q

Chlamidia test

A

NAAT

48
Q

Chlamydia trachomatis serotypes

A

A-C: I cant see
D-K (dick): STI
L1-L3: LGV (Lymph

49
Q

Chlamydia pneumonia in infant cough

A

“stochato” aka short burst

50
Q

Trachoma blindness from

A

Chlamdia A-C

51
Q

Chlamydia complications

A

PID

Reiter syndrome

52
Q

Reiter syndrome

A

Chlamydia affecting eyes genitals and joints

Cant see, cant pee, cant climb a tree

53
Q

Chamydophila psittaci signs and spread

A

Spread by birds

Fevers, chills, pneumonia

54
Q

Why is ricketsia intracellulrar

A

Cant make Coa

Cant make NAD+

55
Q

Ricketsia morph

A

Weak gram neg coccobacillus

56
Q

Rickettsia test

A

Weil-felix

Tests for agglutination

57
Q

Ricketsia sx

A

Headache, fever, vasculitis

58
Q

Ricketsia treatment

A

Doxycycline

59
Q

Ricketsia prowaseki rash progression

A

From trunk to extremities

Spares hands feet head

60
Q

Ricketsia prowaseki spread via

A

Louse

61
Q

Ricketsia prowaseki is cause of

A

Epidemic typhus

62
Q

Ricketsia prowaseki symptoms

A

Rash, Myalgia, arthralgia, encephalitis, pneumonia

63
Q

Rickettsia rickettsii disease

A

Rocky mountain spotted fever

64
Q

Rickettsia rickettsii transmission

A

Dermacentor tick

65
Q

Rocky mountain fever rash spread

A

From extremities inward

66
Q

Rocky mountain spotted fever symptoms

A

Inward rash

Myalgia

Arthralgia

67
Q

Influenza virus morphology

A

SS RNA negative sense virus , has capsid

68
Q

Influenza requires

A

Reverse RNA polymeraze

69
Q

Where does influenza replicate

A

Neclues

70
Q

How many segments in influenza virus

A

8

71
Q

Antigenic variation in flu due to

A

Segments remixing

72
Q

Influenza virulence factors

A

HA hemagluttinin: gets in

Neuromaninidase: Gets out

73
Q

M2 protein in virus does

A

Modulates pH

74
Q

Flu vaccines types

A

Nasal is live

IM is dead

75
Q

Influenza pneumonia characteristic

A

co-infection with S. Auerus or other bugs

76
Q

Malassezia furfur prep and appearance

A

KOH prep
Spaghetti and meatball appearance

77
Q

Malassezia furfur causes

A

Hypo/Hyper pigmented patches with no other symptoms

78
Q

Malassezia furfur layer

A

Most superficial

Stratum corneum

79
Q

Malassezia furfur seen in which neonates

A

Those that get TPN

80
Q

Malassezia furfur treat with

A

selenium sulfide

81
Q

Tinea aka

A

Ringworm

82
Q

Woods lamp diagnoses

A

Microsporum

83
Q

How is nail fungus treated

A

Griseofulvin

84
Q

Sporothrix schenkii morph

A

Dimorphic fungus

Yeast looks like cigar

85
Q

Sporothrix schenkii spread along body

A

Ascending lymphatic

86
Q

Sporothrix schenkii biopsy

A

Histocyte

Giant cells

cigar shaped yeast

87
Q

Sporothrix schenkii treatment

A

Itraconazole

88
Q

Fungus causing verrucous lesions

A

Madurella mycetomatis

89
Q

Organisms that cause tinea

A

Dermatophytes

Microsporum
Truchophyton
Epidemophyton

PBL 2.2.4 (13 decks)

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