Microbiology and the Skin 2

Question 1

Why is paravirus B19 associated with spontaneous abortion?

Answer 1

Causes a low red cell count

Question 2

How will children infected with Paravirus B19 present?

Answer 2

Often looking well

With red cheeks (hence, slapped cheek disease)

Question 3

Which condition does paravirus B19 cause?

Answer 3

Erythema infectiosum

(slapped cheek disease)

Question 4

What remains present as Varicella zoster virus remains dormant?

Answer 4

Viral DNA and transcribed RNA

(in dorsal root ganglia)

Question 5

How is the presentation of shingles different to chicken pox?

Answer 5

Shingles has a dermatomal presentation

Question 6

If HSV1 spreads to atopic eczema which condition can it cause?

Answer 6

Eczema herpeticum

Question 7

How is HSV treated?

Answer 7

Aciclovir

Question 8

Which microorganism is responsible for causing chicken pox and shingles?

Answer 8

Varicella zoster virus

Question 9

What is herpangina and which microorganisms can cause it?

Answer 9

A painful mouth infection causing blisters

Coxsackie A and B viruses

Echoviruses

Question 10

Hand, foot and mouth disease is caused by which virus?

Answer 10

Enteroviruses

Question 11

What is a very severe side effect of hand, foot and mouth disease?

Answer 11

Brain stem encephalitis

Question 12

List treatment options for common warts

Answer 12

1. Cryotherapy
2. Retinoid cream
3. Surgery
4. Topical salicylic acid

Question 13

What causes Lyme disease?

Answer 13

Bacterial infection

(through parasitic vector - ticks)

Question 14

What are the serious late presentations of Lyme disease?

Answer 14

1. Nerve palsies
2. Arthritis
3. Heart block

Question 15

What is the first line therapy for syphilis?

Answer 15

Penicillin

Question 16

Which strain of HSV will cause mouth ulcers most commonly?

Answer 16

HSV1

Question 17

What is the pain associated with shingles that lasts after the blistering and rash disappear?

Answer 17

Postherpetic neuralgia

Question 18

How does aciclovir function?

Answer 18

Stops viral RNA production

(does not destroy virus)

Question 19

What is the treatment for shingles when it presents within 48 hours of symptom onset?

Answer 19

1. Aciclovir 800mg 5x daily for 7-10 days
2. Tramadol 50mg 4x daily

Question 20

Which type of pain is associated with shingles?

Answer 20

Neuropathic

(burning and sharp)

Question 21

Which condition often affects farmers or people in contact with animals such as sheep/goats and causes a large warty lesion on the skin?

Answer 21

Orf

Question 22

Which things is erythema multiforne associated with?

Answer 22

1. Drug reactions
2. HSV
3. Mycoplasma pneumoniae

Question 23

Which microorganism causes common warts?

Answer 23

Human papilloma virus (HPV)

Question 24

Which condition presents which a characteristic bullseye rash?

Answer 24

Lyme disease

Question 25

Which microorganism is responsible for the Zika virus?

Answer 25

Aedes aegypti

Question 26

What does the Zika virus cause in adults?

Answer 26

1. Mild fever 2. Macropapular rash 3. Headaches 4. Arthralgia 5. Myalgia 6. Non-purulent conjunctivitis

Question 27

What does the Zika virus cause in babies born to infected mothers?

Answer 27

1. Microcephaly 2. Guillian-Barre syndrome

Question 28

What are the main complications associated with chicken pox?

Answer 28

1. Encephalitis 2. Pneumonitis 3. Scarring 4. Secondary bacterial infection

Question 29

How is the dermatological presentation of secondary syphilis infection different from chicken pox?

Answer 29

Palms and soles are affected

Question 30

How are the mucosal membranes impacted in secondary syphilis?

Answer 30

Snail-trail ulcers

Question 31

Describe the lesions associated with molluscum contagiosum

Answer 31

1. Fleshy 2. Firm 3. Umbilicated 4. 1-2mm in diameter 5. **Pearlescent**

Question 32

Which age of patient is usually associated with molluscum contagiosum?

Answer 32

Children

Question 33

Which microorganism is responsible for primary gingivostomatitis?

Answer 33

HSV1

Question 34

What age of patients are commonly affected by primary gingivostomatitis and how do they present?

Answer 34

Children (first year of life) No symptoms other than extensive ulceration in and around mouth, not eating and drooling

Question 35

Why do satellite lesions occur in patients with primary gingivostomatitis?

Answer 35

Drroling often occurs and the virus is present in saliva Saliva present on other areas of skin causes satellite lesions

Question 36

What is first line treatment for Lyme disease?

Answer 36

Doxycycline

Question 37

Which microorganism is responsible for Lyme disease?

Answer 37

Borrelia burgdorferi

Question 38

Which condition characteristically presents with a single ulcer at the site of infection?

Answer 38

Primary syphilis

Question 39

Which bacterial species causes syphilis?

Answer 39

Treponema pallidum