Microbiology and the Skin 2 Flashcards

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1
Q

Why is paravirus B19 associated with spontaneous abortion?

A

Causes a low red cell count

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2
Q

How will children infected with Paravirus B19 present?

A

Often looking well

With red cheeks (hence, slapped cheek disease)

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3
Q

Which condition does paravirus B19 cause?

A

Erythema infectiosum

(slapped cheek disease)

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4
Q

What remains present as Varicella zoster virus remains dormant?

A

Viral DNA and transcribed RNA

(in dorsal root ganglia)

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5
Q

How is the presentation of shingles different to chicken pox?

A

Shingles has a dermatomal presentation

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6
Q

If HSV1 spreads to atopic eczema which condition can it cause?

A

Eczema herpeticum

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7
Q

How is HSV treated?

A

Aciclovir

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8
Q

Which microorganism is responsible for causing chicken pox and shingles?

A

Varicella zoster virus

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9
Q

What is herpangina and which microorganisms can cause it?

A

A painful mouth infection causing blisters

Coxsackie A and B viruses

Echoviruses

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10
Q

Hand, foot and mouth disease is caused by which virus?

A

Enteroviruses

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11
Q

What is a very severe side effect of hand, foot and mouth disease?

A

Brain stem encephalitis

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12
Q

List treatment options for common warts

A
  1. Cryotherapy
  2. Retinoid cream
  3. Surgery
  4. Topical salicylic acid
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13
Q

What causes Lyme disease?

A

Bacterial infection

(through parasitic vector - ticks)

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14
Q

What are the serious late presentations of Lyme disease?

A
  1. Nerve palsies
  2. Arthritis
  3. Heart block
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15
Q

What is the first line therapy for syphilis?

A

Penicillin

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16
Q

Which strain of HSV will cause mouth ulcers most commonly?

A

HSV1

17
Q

What is the pain associated with shingles that lasts after the blistering and rash disappear?

A

Postherpetic neuralgia

18
Q

How does aciclovir function?

A

Stops viral RNA production

(does not destroy virus)

19
Q

What is the treatment for shingles when it presents within 48 hours of symptom onset?

A
  1. Aciclovir 800mg 5x daily for 7-10 days
  2. Tramadol 50mg 4x daily
20
Q

Which type of pain is associated with shingles?

A

Neuropathic

(burning and sharp)

21
Q

Which condition often affects farmers or people in contact with animals such as sheep/goats and causes a large warty lesion on the skin?

A

Orf

22
Q

Which things is erythema multiforne associated with?

A
  1. Drug reactions
  2. HSV
  3. Mycoplasma pneumoniae
23
Q

Which microorganism causes common warts?

A

Human papilloma virus (HPV)

24
Q

Which condition presents which a characteristic bullseye rash?

A

Lyme disease

25
Q

Which microorganism is responsible for the Zika virus?

A

Aedes aegypti

26
Q

What does the Zika virus cause in adults?

A
  1. Mild fever
  2. Macropapular rash
  3. Headaches
  4. Arthralgia
  5. Myalgia
  6. Non-purulent conjunctivitis
27
Q

What does the Zika virus cause in babies born to infected mothers?

A
  1. Microcephaly
  2. Guillian-Barre syndrome
28
Q

What are the main complications associated with chicken pox?

A
  1. Encephalitis
  2. Pneumonitis
  3. Scarring
  4. Secondary bacterial infection
29
Q

How is the dermatological presentation of secondary syphilis infection different from chicken pox?

A

Palms and soles are affected

30
Q

How are the mucosal membranes impacted in secondary syphilis?

A

Snail-trail ulcers

31
Q

Describe the lesions associated with molluscum contagiosum

A
  1. Fleshy
  2. Firm
  3. Umbilicated
  4. 1-2mm in diameter
  5. Pearlescent
32
Q

Which age of patient is usually associated with molluscum contagiosum?

A

Children

33
Q

Which microorganism is responsible for primary gingivostomatitis?

A

HSV1

34
Q

What age of patients are commonly affected by primary gingivostomatitis and how do they present?

A

Children (first year of life)

No symptoms other than extensive ulceration in and around mouth, not eating and drooling

35
Q

Why do satellite lesions occur in patients with primary gingivostomatitis?

A

Drroling often occurs and the virus is present in saliva

Saliva present on other areas of skin causes satellite lesions

36
Q

What is first line treatment for Lyme disease?

A

Doxycycline

37
Q

Which microorganism is responsible for Lyme disease?

A

Borrelia burgdorferi

38
Q

Which condition characteristically presents with a single ulcer at the site of infection?

A

Primary syphilis

39
Q

Which bacterial species causes syphilis?

A

Treponema pallidum