Clinical Cases of Rash Flashcards
Which condition is characterised by damage and infiltration of the basal layer of the epidermis?
Lichenoid eruptions
Where on the body does pemphigus vulgaris commonly affect?
Scalp, face, axillae and groin
Fine lace-like pattern on the surface of papules and on the buccal mucosa describes which characteristic sign?
Wickham’s striae
Which age group does bullous pemphigoid affect?
Elderly
What may present in the early stages of bullous pemphigoid?
Urticated itchy patches
What is the main difference between rosacea and acne?
Rosacea does not involve comedones
How is bullous pemphigoid treated?
Systemic steroids
(potentially oral tetraycline as adjunct)
In which condition are steroids generally avoided as part of treatment?
Rosacea
What will a skin biopsy show in a patient with pemphigus vulgaris?
Acantholysis
Which investigations will be undertaken for either bullous pemphigoid or pemphigus vulgaris?
Indirect immunofluorescence
Skin biopsy (with direct immunofluorescence) - to detect IgG at the relevant skin boundary
In which condition (pemphigus or pemphigoid) is mucosal involvement very common?
Pemphigus vulgaris
(rare in pemphigoid)
When treating psoriasis, which medication is given alongside UVA treatment to make the skin temporarily sensitive to the UVA radiation?
Psoralen
Which type of psoriasis is most common in young adults?
Guttate
What is the preferred treatment for psoriasis?
Vitamin D analogues such as calcipotriol or calcitriol
Which type of psoriasis can develop in acral regions and has acute presentation?
Palmoplantar
