Microbiology 6s - Zoonoses

Question 1

clinical presentation and management of Campylobacter

Answer 1

Bloody diarrhoea, bloating cramps,

Supportive mx

Question 2

salmonella reservoir

Answer 2

chicken, reptiles and amphibians

Question 3

management of salmonella typhi and paratyphi

Answer 3

Ciprofloxacin or azithromycin

Question 4

cause of cat scratch fever

Answer 4

bartonella henselae

Question 5

reservoir for bartonella henselae

Answer 5

kittens > cats

Question 6

presentation of cat scratch fever

Answer 6

macule at site of inoculation, becomes pustular, regional adenoapthy, systemic sx of weight loss, night sweats + fever

Question 7

investigation and management of cat scratch fever

Answer 7

ix: serology
mx: erythromycin + doxycycline

Question 8

what disease does bartonella henselae cause in IMMUNOCOMPROMISED people?

Answer 8

bacillary angiomatosis - can be fatal, systemic effects + bursting of blood vessels

Question 9

what type of organism is toxoplasma

Answer 9

parasite

Question 10

symptoms of toxoplasmosis

Answer 10

fever + adenopathy, still-birth, progressive visual loss, progressive motor loss, progressive hearing loss, progressive cognitive loss, seizures

Question 11

investigations for toxoplasmosis

Answer 11

serology + SABIN FELDMAN DYE TEST

Question 12

management of toxoplasmosis in PCR +ve mother and PCR -ve baby

Answer 12

SPIRAMYCIN (prevents vertical transmission)

Question 13

management of toxoplasmosis in PCR +VE mother and PVR +VE baby

Answer 13

Pyrimethamine + sulfadiazine (treat baby for up to 1 year after delivery)

Question 14

brucellosis reservoir

Answer 14

cattle and goats (lives in udders and milk) - transmitted by unpasteurised milk etc

Question 15

brucellosis sx

Answer 15

FLAWS, back pain, orchitis, focal abscesses e.g. psoas, liver

Question 16

what medium should blood/pus be cultured on in brucellosis?

Answer 16

CASTANEDA MEDIUM

Question 17

WHAT IS Q fever caused by ?

Answer 17

Coxiella burnetii

Question 18

clinical presentation of Q fever

Answer 18

Fever, endocarditis, pneumonia, hepatitis, focal abscesses

Atypical pneumonia symptoms: fever dry cough, pleural effusions

Question 19

management of brucellosis

Answer 19

doxyclince + gentamicin

Question 20

management of Q fever

Answer 20

doxycycline

Question 21

name of virus causing rabies

Answer 21

Lyssa virus

Question 22

negri bodies in nerve cells

Answer 22

rabies

Question 23

management of viral haemorrhagic fever

Answer 23

supportive

Question 24

exampels of haemorrhagic fevers

Answer 24

ebola, Marburg, lassa fever, crimean-congo haemorrhagic fever (CCHF)

Question 25

Lassa fever reservoir

Answer 25

rat

Question 26

reservoir of rabies virus

Answer 26

dogs, bats, cats

Question 27

spirillum minus + streptobacillus moniliformis - which zoonoses?

Answer 27

rat bite fever

Question 28

1. A 35 year old presents with a psoas abscess after brucella infection, what is first investigation?

Answer 28

Blood culture (Can also do serology but takes longer)

Question 29

2. A 35 year old pt presents with fever after return from Rwanda, co-habited in a hut with family and livestock. what do you do?

Answer 29

Admit to side room

Question 30

definition of zoonoses

Answer 30

infections which are transmitted naturally between vertebrate animals and humans

Question 31

swimming, conjunctival haemorrhages, sewage worker

Answer 31

Leptospirosis