Microbiology Flashcards

1
Q

Combination therapy of tuberculosis

A
2 months of:
 Rifampicin
 Isoniazid
 Pyrazinamide
 Ethambutol
4 months of:
 Rifampicin
 Isoniazid
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2
Q

What effect does rifampicin have on urine?

A

Colours urine and all bodily fluids orange

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3
Q

Antibiotic given for pleural infection

A

Vancomycin (for s.aureus)

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4
Q

Nasopharynx host defences

A

Nasal hairs
Ciliated epithelia
IgA

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5
Q

Oropharynx host defences

A

Saliva
Sloughing
Cough

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6
Q

Sinusitis

A

Inflammation of paranasal sinuses

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7
Q

Rhinitis

A

Inflammation of nose

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8
Q

Pharyngitis

A

Inflammation of pharynx, tonsils, uvula

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9
Q

Epiglottitis

A

Inflammation of epiglottis, superior larynx

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10
Q

Laryngitis

A

Inflammation of larynx

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11
Q

Gram positive upper respiratory tract colonisers

A
Strep pneumoniae (a-haemolytic streptococci)
Strep pyogenes (b-haemolytic streptococci)
Staphylococcus aureus
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12
Q

Gram negative upper respiratory tract colonisers

A

Haemophilus influenzae

Moraxella Catarrhalis

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13
Q

Haemophilus influenzae

A

Gram negative coccobacillus

Blood-loving species

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14
Q

Moraxella Catarrhalis

A

Gram negative coccus

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15
Q

Conducting airway defences

A

Mucociliary escalator
AMPs
Cellular and humoral immunity

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16
Q

Bacteria which causes whooping cough

A

Bordetella Pertussis

17
Q

Characteristics of bordetella pertussis

A

Gram negative coccobacillus

Exclusively human pathogen

18
Q

3 main routes of transmission

A

Contact
Airborne
Droplets

19
Q

Lower respiratory tract defences

A

Alveolar lining fluid - IgA, AMP, Surfactant, Complement, FFA
Alveolar macrophages and neutrophils

20
Q

Causative organisms for community acquired pneumonia

A

Streptococcus pneumoniae
Atypicals/ Viruses
Haemophilus influenzae
Staphylococcus aureus

21
Q

Treatment for legionella pneumonia

A

Clarythromycin, erythryomycin

Qunolone (e.g. levofloxacin)

22
Q

Legionella pneumonia characteristics

A

Common environmental gram negative bacteria
Resides with water amoeba
Invades alveolar macrophages& replicates

23
Q

Clinical presentation of legionella pneumonia

A

Flu like illness which may progress to severe pneumonia
Mental confusion
Renal failure
GI problems