Microbial Diseases Of Skin And Wounds Pt. 1 Flashcards

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0
Q

What is the term for a small abscess?

A

Pimple (not the acne kind)

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1
Q

What is a pus-filled pocket in the skin resulting from bacterial infection that can occur on the surface or within deeper structures of the skin?

A

Abscess

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2
Q

What type of abscess is a large, painful, raised nodular extension of folliculitis into surrounding tissue?

A

Furuncle or boil

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3
Q

What is the term for a coalescence of several furuncles that can extend into deep tissues and possibly involve the organ systems?

A

Carbuncle

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4
Q

What is a type of skin abscess that involves the hair follicle?

A

Folliculitis

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5
Q

What is an abscess at the eyelid base?

A

Sty

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6
Q

What are the symptoms of abscesses?

A

Red, itching, burning, drainage of either blood or pus (or both)

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7
Q

What genus of pathogens is most commonly the cause of abscesses/folliculitis?

A

Staphylococcus

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8
Q

What two species are commonly found on the skin and can be involved with abscesses?

A

Staphylococcus epidermidis and staphylococcus aureus

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9
Q

What is the most predominant pathogen on the skin?

A

Staphylococcus epidermidis

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10
Q

Which pathogen is most likely to be the the cause of infection for abscesses/folliculitis even though it isn’t the most predominant one on the skin?

A

Staphylococcus aureus

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11
Q

How are abscesses typically acquired?

A

Direct contact/fomites, often auto-inoculation

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12
Q

What is the diagnosis for abscesses?

A

Isolation of bacteria in grape-like clusters from pus

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13
Q

What is the treatment for abscesses?

A

May heal on its own in about two weeks, but warm compresses can help with itching, swelling and natural draining. Medical intervention would involve professional draining or antibiotics.

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14
Q

How can abscesses be prevented?

A

Hand washing, proper procedures in hospitals to minimize MRSA infections

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15
Q

What pathogen causes “hot tub folliculitis”?

A

Pseudomonas aeruginosa

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16
Q

What activity can cause “hot tub folliculitis” to develop?

A

After using a poorly chlorinated hot tub or spa (appears 6 hours-5 days after)

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17
Q

What are signs of “hot tub folliculitis”?

A

Many small “pimples” on stomach, buttocks, arms, and legs

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18
Q

Can “hot tub folliculitis” self-resolve?

A

Yes, in about 7-10 days

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19
Q

What are the signs and symptoms of staphylococcal scalded skin syndrome?

A

Reddening of the skin beginning near the mouth and spreading over the entire body, eventual large blisters where (after about 2 days) outer layer of skin falls off in sheets

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20
Q

What is unique about the blisters formed in staphylococcal scalded skin syndrome?

A

Lacks white blood cells and bacteria

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21
Q

What is a huge risk for those with staphylococcal scalded skin syndrome once the outer layer of skin has fallen off?

A

Risk for secondary bacterial infections

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22
Q

What is the pathogen usually to blame for staphylococcal scalded skin syndrome?

A

Some staphylococcus aureus strains

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23
Q

Staphylococcal scalded skin syndrome is more likely to affect what population?

A

Infants

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24
Q

What disease can be largely mistaken for child abuse due to the appearance of blisters and the entire body appearing like it was dipped in boiling water?

A

Staphylococcal scalded skin syndrome

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25
Q

How is staphylococcal scalded skin syndrome usually transmitted?

A

Person to person contact

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26
Q

What is the diagnosis for staphylococcal scalded skin syndrome?

A

Sloughing of the skin

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27
Q

What is the treatment for staphylococcal scalded skin syndrome?

A

Administration of IV antibiotics usually requiring hospitalization in the burn unit

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28
Q

Why is prevention of staphylococcal scalded skin syndrome difficult?

A

Large presentation of staphylococcus strains on the skin naturally

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29
Q

What are the signs and symptoms of impetigo?

A

Small, flattened red patches on face and limbs that develop into pus-filled vesicles that crust

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30
Q

What is another name for impetigo?

A

Pyoderma (pyo- = fiery)

31
Q

What skin condition involves pus filled vesicles affecting the top layers of the skin?

A

Impetigo

32
Q

What is the composition of the pus involved with impetigo?

A

Filled with bacteria and white blood cells (compare to those of staphylococcal scalded skin syndrome)

33
Q

What are the signs and symptoms for erysipelas?

A

Hot, red skin with a fiery red rash with raised borders

34
Q

What is the most common location for erysipelas?

A

Legs (80%)

35
Q

What pathogen causes 80% of the cases of impetigo?

A

Staphylococcus aureus

36
Q

What pathogen causes 80% of the cases of erysipelas?

A

Streptococcus pyogenes

37
Q

What is the peak age of incidence of erysipelas?

A

Ages 60-80 (elderly)

38
Q

What three groups are more likely to develop erysipelas?

A

Infants, young children, and elderly (compromised immune systems)

39
Q

What pathogen causes 20% of erysipelas?

A

Staphylococcus aureus

40
Q

What pathogen causes 20% of impetigo?

A

Streptococcus pyogenes

41
Q

What is the clinical term for the flesh-eating disease?

A

Necrotizing fasciitis

42
Q

What organism is responsible for necrotizing fasciitis and is known as the “flesh-eating bacteria”?

A

Streptococcus pyogenes

43
Q

What very serious condition involves streptococci entering the body through breaks in the skin that secrete enzymes and toxins destroy tissue?

A

Necrotizing fasciitis

44
Q

What is the fatality rate for necrotizing fasciitis?

A

Over 50%

45
Q

What are some signs of necrotizing fasciitis?

A

Big purplish-red blisters that eventually destroy muscle and fat tissue

46
Q

How is necrotizing fasciitis usually spread?

A

Person to person via breaks in the skin

47
Q

How is necrotizing fasciitis treated?

A

IV antibiotics and can often lead to amputation surgery

48
Q

Why is early diagnosis of necrotizing fasciitis difficult?

A

Symptoms are nonspecific

49
Q

Necrotizing fasciitis travels along what structure of the body during its course of destroying tissue?

A

Along fascia

50
Q

What is a pustule?

A

A blister-like area full of pus common with severe cases of acne

51
Q

What is the organism responsible for acne?

A

Propionibacterium acnes

52
Q

Acne is seen among what percent of adolescents and young adults?

A

85%

53
Q

Why is acne so common?

A

The pathogen responsible for it is a part of normal microbiota

54
Q

What is a long term treatment for acne?

A

Tetracycline

55
Q

What are the signs and symptoms of Cat Scratch Disease?

A

Bump (papule) or blister (pustule) at the site of injury as a first sign followed by lymphadenopathy near the area, fatigue, fever, headache, malaise

56
Q

What is the pathogen responsible for Cat Scratch Disease?

A

Bartonella henselae

57
Q

How is Cat Scratch Disease transmitted?

A

Cat bites or scratches

58
Q

How is Cat Scratch Disease diagnosed and treated?

A

Serological testing, treated with antibiotics

59
Q

What substance is to blame for the tissue damage associated with Pseudomonas infection?

A

Production of pyocyanin (blue-green in color)

60
Q

What are the signs and symptoms of Pseudomonas infections?

A

Fever, chills, and the production of purulent matter in infected wounds

61
Q

A population of individuals with what other ailment are more at risk for Pseudomonas infections?

A

Severe burns (2/3 of burn victims)

62
Q

What is the most common causative agent of Pseudomonas infection?

A

Pseudomonas aeruginosa

63
Q

Where can Pseudomonas aeruginosa be found?

A

Soil, decaying matter, moist environments

64
Q

Why is Pseudomonas infection difficult to treat?

A

Due to multidrug resistance of Pseudomonas aeruginosa

65
Q

How can Pseudomonas infection be diagnosed?

A

Only at the severe stages when pyocyanin discoloration occurs indicating massive infection

66
Q

What are the signs and symptoms of Rocky Mountain Spotted Fever that develop a week after infection?

A

Flu like symptoms, followed by a non-itchy spotted rash on trunk and appendages, soles and palms (90% of infected individuals), petechiae in 50%

67
Q

Severe cases of Rocky Mountain Spotted Fever develop what adverse conditions?

A

Respiratory, CNS, GI, and renal system failure

68
Q

What is the pathogen responsible for Rocky Mountain Spotted Fever?

A

Rickettsia rickettsii

69
Q

What is the most severe and most common Ricketsial illness?

A

Rocky Mountain Spotted Fever

70
Q

What is the reservoir for Rickettsia rickettsii?

A

Rodents

71
Q

What is the vector responsible for the transmission to humans of Rickettsia rickettsii?

A

Tick (bites)

72
Q

When are cases of Rocky Mountain Spotted Fever usually reported to the CDC?

A

During the summer (peak in June and July)

73
Q

What is the fatality rate for Rocky Mountain Spotted Fever?

A

5% with or without treatment

74
Q

What is the treatment for Rocky Mountain Spotted Fever?

A

Removal of the tick (preferably before 24 hours) and antibiotics