Microbial control and pathogenesis of infection Flashcards
device that encloses a working area to protect workers from aerosol exposure
BSC
BSC:
-allow room air to pass into cabinet
-negative pressure
-used for BSL 2,3 agents
class 1
BSC:
-aka. laminar flow BSC
-most hospital clinical microbiology laboratory use
-use for BSL 2,3 agents
class 2
BSC:
provide most protection to the worker-highest level of safety
-air coming in and out is sterilized
class 3
classification of biologic agents:
-no known potential for infecting healthy people
-for students
BSL 1
classification of biologic agents:
bacillus subtilis
mycobacterium gordonae
naegleria gruberi
BSL 1
classification of biologic agents:
-agents acquired by ingestion, pecutaneous, mucous-membrane
-common agents of infectious diseases
-PPE and immunization required
BSL 2
classification of biologic agents:
HIV
bacillus anthracis
yersinia pestis
toxoplasma
salmonella
shigella
BSL 2
classification of biologic agents:
-agents for aerosol transmission, lethal pathogens
-indigenous or toxic
BSL 3
classification of biologic agents:
mycobacterium tuberculosis
systemic fungi
francisella tuleransis
brucella spp
coxiella burnetti
st. louis encephalitis virus
BSL 3
classification of biologic agents:
-dangerous and exotic
-cause life-threatening inections
-maximum containment and decontamination should be observed
BSL 4
classification of biologic agents:
arbovirus
arenavirus
filovirus
small pox virus
BSL 4
category of potential infectious agents of bioterrorism:
-greatest public health threat
-easily transmitted and highly infectious
category A agents
category of potential infectious agents of bioterrorism:
small pox
anthrax
tularemia
category A agents
category of potential infectious agents of bioterrorism:
-moderate morbidity and low mortality
-not as easily transmitted
category B agents
category of potential infectious agents of bioterrorism:
coxiella burnetti
burkholderia pseudomalei
rickettsia
category B agents
category of potential infectious agents of bioterrorism:
emerging pathogens
category C agents
category of potential infectious agents of bioterrorism:
yellow fever
dengue fever
hemorrhagic fever
category C agents
all clinical laboratories must adhere to BSL – guidelines
BSL 2
specimen processing from possible bioterrorism event should occur within BSC class
BSC class 2
5 most frequently acquired laboratory infections:
shigellosis
salmonellosis
tuberculosis
brucellosis
hepatitis
