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Micro Remediation > Micro Summary: Treatment > Flashcards

Micro Summary: Treatment Flashcards

1
Q

Bacteriodes: Bacilus, Prevotella, Porphoryngeus

A

Drainage, TFM

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2
Q

Histotoxic Clostridia: C. perfringens, C. septicum

A

Surgery, amputation

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3
Q

C. tetani

A

Antitoxin

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4
Q

C. botulism

A

Antitoxin

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5
Q

C. difficile

A

Metronidazole (oral or IV) or oral vancomycin (but NOT IV)

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6
Q

Haemophilus influenzae

A

Cephalosporins & amoxicillin/clavulanate, rifampin (carriers), Hilleman’s vaccine

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7
Q

Mycoplasma pneumoniae

A

TFM, azithromycin (prophylaxis)

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8
Q

Klebsiella

A

All produce SHV-type beta-lactamase (Resistant to ampicillin), Some produce ESBL (Resistant to all beta-lactams except carbapenems), Some produce K. pneumoniae carbapenemase (KPC) beta-lactamase (Resistant to all beta-lactams including carbapenems)

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9
Q

Yersinia pestis

A

Streptomycin (& gentamicin, doxycycline, ciprofloxacin)

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10
Q

Chlamydia trachomatis

A

Normal: azitrhomycin & doxycycline, Pregnant: azitrhomycin & amoxicillin, LGB: doxycycline

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11
Q

Treponema pallidum

A

Early/Late: benzathine PCN G & doxycycline, Neurosyphilis: crystalline PCN G, Pregnant: PCN (desensitize)

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12
Q

Rickettsia rickettsii

A

Doxycycline

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13
Q

Borrelia burgdorferi

A

Early: doxycycline, amoxicillin, Late: IV ceftriaxone

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14
Q

Bacillus anthracis

A

Cutaneous: doxycycline or ciprofloxacin,Inhalational/GI: Ciprofloxacin, linezolid, Meropenem (meningitis), Clindamycin (no meningitis), Post-exposure prophylaxis: vaccine, doxycycline, levofloxacin, ciprofloxacin, Raxibacumab, pleural effusion drainage, vaccine

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15
Q

Francisella tularensis

A

Streptomycin (& gentamicin, doxycycline)

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16
Q

Helicobacter pylori

A

> 1 antimicrobial (e.g., clarithromycin and bismuth salts) and an acid blocker (e.g., omeprazole)

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17
Q

Enterococcus faecium

A

Linezolid and daptomycin against vancomycin resistant Enterococci (VRE)

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18
Q

Staphylococcus aureus

A

Vancomycin, linezolid, daptomycin

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19
Q

Neisseria meningitidis

A

Penicillins, Cephalosporins, FQs

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20
Q

Neisseria gonorrhoeae

A

Cephalosporins (ceftriaxone)

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21
Q

Streptococcus pyogenes

A

Penicillins, Beta-lactams

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22
Q

Streptococcus pneumoniae

A

Beta-lactams

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23
Q

Listeria monocytogenes

A

Ampicillin or TMP/SMX

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24
Q

Legionella pneumophila

A

Macrolides, quinolones

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25
Mycobacterium tuberculosis
BCG vaccine, rifampin, isoniazid, pyrazinamide, ethamutol, FQs (moxi, second line)
26
Mycobacterium leprae
Dapsone, rifampin
27
Corynebacterium diphtheria
Antitoxin, DPT vaccine, erythromycin, penicillin
28
Vibrio cholera
Oral vaccines (O1, O139, B-subunit recombinants), restore fluid/electrolyte balance, oral rehydration solution, azithromycin
29
Bordetella pertussis
Purified diptheria and tetanus toxoid proteins (DPT), acellular version (DtaP), adverse reactions much lower
30
Candida albicans
Nystatin, azoles | Azoles, echinocandins, amphotericin B
31
Cryptococcus neoformans & gattii
Amphotericin + 5-flucytosine then fluconazole
32
Dermatophytes
Topical (imidazoles), oral (terbinafine, azoles)
33
Pneumocystis jiroveci
TMP/SMX (prevention)
34
Aspergillus fumigatus & niger
Amphotericin, voriconazole, posaconazole, itraconazole, or echinocandins, but NOT fluconazole
35
Zygomycoses: mucor, absidia, rhizopus, rhizomucor
Amphotericin B, posaconazole, surgical resection
36
Histoplasma capsulatum
Amphotericin, itraconazole
37
Entamoeba histolytica
Metronidazole
38
Acanthamoeba
Metronidazole
39
Giardia lamblia
Metronidazole
40
Cryptosporidium
Nitazoxanide
41
Trichomonas vaginalis
Metronidazole
42
Plasmodium falciparum
Erythrocytic (chloroquine, quinine), Exoerythrocytic (primaquine), Resistance (artemisinin, mefloquine, atovaquone / proguanil)
43
Ascaris lumbricoides
Albendazole, Mebendazole, Ivermectin
44
Pinworm (Enterobius vermicularis)
Albendazole, Mebendazole, Pyrantel
45
Strongyloides stercoralis
Albendazole, Mebendazole, Ivermectin
46
Whipworm (trichuris trichiura)
Albendazole, Mebendazole, Ivermectin
47
Onchocerca, Wuchereria, Brugia
Ivermectin
48
Schistosoma hepatobium, japonicum, & mansoni
Praziquantel
49
Taenia solium
Albendazole, Mebendazole
50
Echinococcus granulosus
Albendazole, Mebendazole
51
Poliovirus
Salk vaccine (IPV), Sabin vaccine (OPV), Pleconaril
52
HAV
HAIG, vaccine
53
HBV
HBIG, vaccine, Interferon, Lamivudine, Emtricitabine Tenofovir, Telbivudine, Entecavir, Adefovir
54
HCV
Interferon, Ribavirin, Boceprevir, Teleprevir, Sofosbuvir
55
HDV
HBV vaccine, Interferon-alpha
56
HSV
ART: acyclovir, penciclovir
57
HPV
opical agents, cryotherapy, surgery, inferferons, vaccination (quadrivalent & bivalent)
58
VZV
Acyclovir, live attenuated vaccine
59
Adenovirus
Cidofovir, vaccine
60
Hantavirus
IV fluid, dialysis
61
Rabies
Pre- or post-exposure rabies prophylaxis (PEP): wound cleansing, human rabies immune globulin (HRIG), HDCV
62
Smallpox
Cidofovir, Vaccine
63
VHFs
Ribavirin (arena)
64
EBV
Acyclovir, ganciclovir, CTL therapy, anti-CD20 therapy, decrease immunosuppressive therapy
65
Influenza
amantadine & rimantadine (for influenza A, interacts w/ M2 protein), oseltamivir & zanamivir (neuraminidase inhibitors), vaccine
66
Mumps
Attenuated vaccine grown in chick embryo cell culture
67
Measles
Live attenuated vaccine
68
Rubella
Live attenuated vaccine, Prevent congenital rubella by controlling postnatal rubella

Micro Remediation (30 decks)

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