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Micro Remediation > Micro Summary: Treatment > Flashcards

Micro Summary: Treatment Flashcards

1
Q

Bacteriodes: Bacilus, Prevotella, Porphoryngeus

A

Drainage, TFM

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2
Q

Histotoxic Clostridia: C. perfringens, C. septicum

A

Surgery, amputation

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3
Q

C. tetani

A

Antitoxin

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4
Q

C. botulism

A

Antitoxin

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5
Q

C. difficile

A

Metronidazole (oral or IV) or oral vancomycin (but NOT IV)

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6
Q

Haemophilus influenzae

A

Cephalosporins & amoxicillin/clavulanate, rifampin (carriers), Hilleman’s vaccine

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7
Q

Mycoplasma pneumoniae

A

TFM, azithromycin (prophylaxis)

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8
Q

Klebsiella

A

All produce SHV-type beta-lactamase (Resistant to ampicillin), Some produce ESBL (Resistant to all beta-lactams except carbapenems), Some produce K. pneumoniae carbapenemase (KPC) beta-lactamase (Resistant to all beta-lactams including carbapenems)

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9
Q

Yersinia pestis

A

Streptomycin (& gentamicin, doxycycline, ciprofloxacin)

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10
Q

Chlamydia trachomatis

A

Normal: azitrhomycin & doxycycline, Pregnant: azitrhomycin & amoxicillin, LGB: doxycycline

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11
Q

Treponema pallidum

A

Early/Late: benzathine PCN G & doxycycline, Neurosyphilis: crystalline PCN G, Pregnant: PCN (desensitize)

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12
Q

Rickettsia rickettsii

A

Doxycycline

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13
Q

Borrelia burgdorferi

A

Early: doxycycline, amoxicillin, Late: IV ceftriaxone

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14
Q

Bacillus anthracis

A

Cutaneous: doxycycline or ciprofloxacin,Inhalational/GI: Ciprofloxacin, linezolid, Meropenem (meningitis), Clindamycin (no meningitis), Post-exposure prophylaxis: vaccine, doxycycline, levofloxacin, ciprofloxacin, Raxibacumab, pleural effusion drainage, vaccine

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15
Q

Francisella tularensis

A

Streptomycin (& gentamicin, doxycycline)

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16
Q

Helicobacter pylori

A

> 1 antimicrobial (e.g., clarithromycin and bismuth salts) and an acid blocker (e.g., omeprazole)

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17
Q

Enterococcus faecium

A

Linezolid and daptomycin against vancomycin resistant Enterococci (VRE)

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18
Q

Staphylococcus aureus

A

Vancomycin, linezolid, daptomycin

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19
Q

Neisseria meningitidis

A

Penicillins, Cephalosporins, FQs

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20
Q

Neisseria gonorrhoeae

A

Cephalosporins (ceftriaxone)

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21
Q

Streptococcus pyogenes

A

Penicillins, Beta-lactams

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22
Q

Streptococcus pneumoniae

A

Beta-lactams

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23
Q

Listeria monocytogenes

A

Ampicillin or TMP/SMX

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24
Q

Legionella pneumophila

A

Macrolides, quinolones

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25
Q

Mycobacterium tuberculosis

A

BCG vaccine, rifampin, isoniazid, pyrazinamide, ethamutol, FQs (moxi, second line)

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26
Q

Mycobacterium leprae

A

Dapsone, rifampin

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27
Q

Corynebacterium diphtheria

A

Antitoxin, DPT vaccine, erythromycin, penicillin

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28
Q

Vibrio cholera

A

Oral vaccines (O1, O139, B-subunit recombinants), restore fluid/electrolyte balance, oral rehydration solution, azithromycin

29
Q

Bordetella pertussis

A

Purified diptheria and tetanus toxoid proteins (DPT), acellular version (DtaP), adverse reactions much lower

30
Q

Candida albicans

A

Nystatin, azoles

Azoles, echinocandins, amphotericin B

31
Q

Cryptococcus neoformans & gattii

A

Amphotericin + 5-flucytosine then fluconazole

32
Q

Dermatophytes

A

Topical (imidazoles), oral (terbinafine, azoles)

33
Q

Pneumocystis jiroveci

A

TMP/SMX (prevention)

34
Q

Aspergillus fumigatus & niger

A

Amphotericin, voriconazole, posaconazole, itraconazole, or echinocandins, but NOT fluconazole

35
Q

Zygomycoses: mucor, absidia, rhizopus, rhizomucor

A

Amphotericin B, posaconazole, surgical resection

36
Q

Histoplasma capsulatum

A

Amphotericin, itraconazole

37
Q

Entamoeba histolytica

A

Metronidazole

38
Q

Acanthamoeba

A

Metronidazole

39
Q

Giardia lamblia

A

Metronidazole

40
Q

Cryptosporidium

A

Nitazoxanide

41
Q

Trichomonas vaginalis

A

Metronidazole

42
Q

Plasmodium falciparum

A

Erythrocytic (chloroquine, quinine), Exoerythrocytic (primaquine), Resistance (artemisinin, mefloquine, atovaquone / proguanil)

43
Q

Ascaris lumbricoides

A

Albendazole, Mebendazole, Ivermectin

44
Q

Pinworm (Enterobius vermicularis)

A

Albendazole, Mebendazole, Pyrantel

45
Q

Strongyloides stercoralis

A

Albendazole, Mebendazole, Ivermectin

46
Q

Whipworm (trichuris trichiura)

A

Albendazole, Mebendazole, Ivermectin

47
Q

Onchocerca, Wuchereria, Brugia

A

Ivermectin

48
Q

Schistosoma hepatobium, japonicum, & mansoni

A

Praziquantel

49
Q

Taenia solium

A

Albendazole, Mebendazole

50
Q

Echinococcus granulosus

A

Albendazole, Mebendazole

51
Q

Poliovirus

A

Salk vaccine (IPV), Sabin vaccine (OPV), Pleconaril

52
Q

HAV

A

HAIG, vaccine

53
Q

HBV

A

HBIG, vaccine, Interferon, Lamivudine, Emtricitabine Tenofovir, Telbivudine, Entecavir, Adefovir

54
Q

HCV

A

Interferon, Ribavirin, Boceprevir, Teleprevir, Sofosbuvir

55
Q

HDV

A

HBV vaccine, Interferon-alpha

56
Q

HSV

A

ART: acyclovir, penciclovir

57
Q

HPV

A

opical agents, cryotherapy, surgery, inferferons, vaccination (quadrivalent & bivalent)

58
Q

VZV

A

Acyclovir, live attenuated vaccine

59
Q

Adenovirus

A

Cidofovir, vaccine

60
Q

Hantavirus

A

IV fluid, dialysis

61
Q

Rabies

A

Pre- or post-exposure rabies prophylaxis (PEP): wound cleansing, human rabies immune globulin (HRIG), HDCV

62
Q

Smallpox

A

Cidofovir, Vaccine

63
Q

VHFs

A

Ribavirin (arena)

64
Q

EBV

A

Acyclovir, ganciclovir, CTL therapy, anti-CD20 therapy, decrease immunosuppressive therapy

65
Q

Influenza

A

amantadine & rimantadine (for influenza A, interacts w/ M2 protein), oseltamivir & zanamivir (neuraminidase inhibitors), vaccine

66
Q

Mumps

A

Attenuated vaccine grown in chick embryo cell culture

67
Q

Measles

A

Live attenuated vaccine

68
Q

Rubella

A

Live attenuated vaccine, Prevent congenital rubella by controlling postnatal rubella

Micro Remediation (30 decks)

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