Micro Final Details Flashcards
Action of the diptheria and pseudomonas exotoxin A
Robosylate and inactivate EF-2 (AB-toxin)
Action of pertussis toxin
Inactivated Gi–> increased cAMP
Impairs phagocytosis
Cleaves snare proteins, inhibiting the release of neurotransmitters
Botlinum (prevent Ach release) and tetnus toxin (prevents GABA relase)
Phospholipase that degrades cell membranes
C. perfringings Alpha Toxin
mechanism of streptolysin O toxin
Lyses RBC
Approximate MHC-II and T-cell receptors resulting in overwhelming release of INF-y and IL-2
S. pyogenes exotoxin A
S. aureus TSST-1
ability to take up naked DNA from the environment and incorporate it into it’s own genome
Transformation
Phage DNA incorportated into bacterial chromosome
Generalized tranduction
Bacterial DNA accidentally incorporated into viral genome when it is excized
Specialized transduction
G (+) Rods
Clostridium (anaerobe) (Cant Breath Air)
Corynebacterium
Listeria
Bacillus (aerobe) (Nagging Pests Must Breath)
Mycobacterium (acid fast)
Binds Fc of IgG preventing complement formation
S. aureus
Protein A
Lancet shaped diplococci with an IgA protease
S. pneumonia
Optochin sensitive
G(+) rods with metachromatic granules
C. diptheriae
Location of GABA inhibition by tetanus toxin
Inhibits SNAREs in the **Renshaw cells **of the GABAercic
neurons of the spinal cord
Drug most commonly responsible for psuedomembranous colitis
Clindamycin and ampicillin