Auto-antibodies Flashcards

1
Q

Anti-IgG antbodies

A

Rheumatoid arthritis (Rhematoid factor)

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2
Q

Anti-citrullinated protein antibodies (anti-ccp)

A

RA

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3
Q

Anti-centromere

A

CREST scleroderma

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4
Q

Anti-Scl-70

A

Diffuse scleroderma

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5
Q

Anti-histone

A

Drug induced lupus

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6
Q

ANA

A

Lupus screening

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7
Q

Anti-smith

A

Lupus

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8
Q

Anti-dsDNA

A

Lupus

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9
Q

Anti-jo-1

A

Polymyositis and dermatomyositis

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10
Q

Anti-SSA (anti-Ro)

A

Sjogren syndrome

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11
Q

Anti-SSB (anti-La)

A

Sjogren syndrome

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12
Q

Anti-U1-RNP

A

Mixed connective tissue

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13
Q

Anti-desmoglein

A

Pemphigus vulgaris

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14
Q

Anti-acetylcholine

A

Myasthenia Gravis

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15
Q

Anti-endomysial (anti-tissue transglutaminase)

A

Celiac disease

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16
Q

Anti-gliadin

A

Celiac disease

17
Q

Anti-mitochondrial

A

Primary biliary cirrhosis

18
Q

Anti-smooth muscle

A

Autoimmune hepatitis

19
Q

Anti-glutamate decarboxylase

A

Type I diabetes mellitus

20
Q

Anti-thyrotropin receptor

A

Graves disease (hyperthyroidism)

21
Q

Anti-thyroid peroxidase

A

Hashimoto thyroiditis

22
Q

Anti-thyroglobulin

A

Graves or Hashimoto

23
Q

Anti-basement membrane

A

Goodpasture syndrome

24
Q

c-ANCA

A

Wegner granulomatosis (graulomatis with polyangiitis)

25
Q

p-ANCA

A

Polyarteritis nodosa (sometimes)
Polyarteritis Nodosa
Churg-strauss syndrome
Pauci-immune crecentic polyangiitis