Auto-antibodies

Question 1

Anti-IgG antbodies

Answer 1

Rheumatoid arthritis (Rhematoid factor)

Question 2

Anti-citrullinated protein antibodies (anti-ccp)

Answer 2

RA

Question 3

Anti-centromere

Answer 3

CREST scleroderma

Question 4

Anti-Scl-70

Answer 4

Diffuse scleroderma

Question 5

Anti-histone

Answer 5

Drug induced lupus

Question 6

ANA

Answer 6

Lupus screening

Question 7

Anti-smith

Answer 7

Lupus

Question 8

Anti-dsDNA

Answer 8

Lupus

Question 9

Anti-jo-1

Answer 9

Polymyositis and dermatomyositis

Question 10

Anti-SSA (anti-Ro)

Answer 10

Sjogren syndrome

Question 11

Anti-SSB (anti-La)

Answer 11

Sjogren syndrome

Question 12

Anti-U1-RNP

Answer 12

Mixed connective tissue

Question 13

Anti-desmoglein

Answer 13

Pemphigus vulgaris

Question 14

Anti-acetylcholine

Answer 14

Myasthenia Gravis

Question 15

Anti-endomysial (anti-tissue transglutaminase)

Answer 15

Celiac disease

Question 16

Anti-gliadin

Answer 16

Celiac disease

Question 17

Anti-mitochondrial

Answer 17

Primary biliary cirrhosis

Question 18

Anti-smooth muscle

Answer 18

Autoimmune hepatitis

Question 19

Anti-glutamate decarboxylase

Answer 19

Type I diabetes mellitus

Question 20

Anti-thyrotropin receptor

Answer 20

Graves disease (hyperthyroidism)

Question 21

Anti-thyroid peroxidase

Answer 21

Hashimoto thyroiditis

Question 22

Anti-thyroglobulin

Answer 22

Graves or Hashimoto

Question 23

Anti-basement membrane

Answer 23

Goodpasture syndrome

Question 24

c-ANCA

Answer 24

Wegner granulomatosis (graulomatis with polyangiitis)

Question 25

p-ANCA

Answer 25

Polyarteritis nodosa (sometimes)
Polyarteritis Nodosa
Churg-strauss syndrome
Pauci-immune crecentic polyangiitis