Mice and rats Flashcards
What percent of the cage volume should be displaced per minute when administering carbon dioxide from a compressed cylinder as a
form of euthanasia for small rodents?
30-70%
Which gene is associated with age-related hearing loss in several mouse strains including C57BL/6J, DBA/2J, NOD/ShiLtJ?
Cadherin23 (Cdh23)
Cdh23^ahl (homozygous)
Azoxymethane induces which condition in mice and rats?
Colorectal cancer
What species are frequently found with ulcerative dermatitis? Which is pathogenic?
Staph aureus - most commonly isolated and pathogenic
Staph epidermidis - nonpathogenic
How much urine can be collected from a manually restrained mouse urinating spontaneously in a 2-minute period?
50-500 uL!
Which mouse is known for being a model of alopecia areata?
C3H
Which nutrient or vitamin concentrations are lowered when diets for mice and rats are autoclaved?
Thiamin (B1), vitamin A, vitamin E, pantothenic acid (B5), pyridoxine (B6), and B12
***A, B, C, E
PCR for which gene will detect both minute virus of mice and mouse parvovirus?
NS-1
What cage material offers superior advantages in terms of heat resistance to autoclaving without damaging viewing of animals?
Polycarbonate
Durability:
Polysulfone > polyetherimide (PEI) > polycarbonate > polypropylene > polystyrene
Mice are inbred after ___ generations but may be considered fully inbred (no residual heterozygosity) after ___ generations.
20; 60
Which rat strain is an animal model for spontaneous Type 1 diabetes mellitus?
BB (BioBreeding)
Is corncob or paper bedding better at preventing ammonia in IVC?
Paper bedding
Exhaust air dust testing is better at detecting ___ than soiled bedding sentinels.
Fur mites
Lymphocytic choriomeningitis virus (LCMV)
Pasteurella pneumotropica
Sendai virus
What type of organism is Spironucleus muris?
Protozoa
What is the most common sign of mucometra in an adult female mouse?
Abdominal distention
T/F Prophylactic antibiotics are considered to be effective at preventing C.
bovis infection in immunocompromised mice
True
