MI Flashcards
Best Discriminator of MI w/n 3 hours of chest pain onset
EKG
Transmural MI, injury and myocardial ischemia
- full thickness
- usually L ventricle 2* to coronary artery disease
MI diagnosis
At least 2 of 3:
- symptoms >20min
- EKG changes (at least 2 leads)
- Enzyme changes
ST Segment Elevation
>6 months =
ventricular aneurysm
After 3 hours best discriminant of MI is
creatine kinase MB
Reciprocal EKG changes
- indicative of large MI
- in leads opposite of TM MI
- change is transient
- ST segment depression with T wave upright
Myocardial Ischemia
- Zone of Ischemia: functioning tissue at periphery of infarct
- T wave increased size & peaked & symmetrical for 1st several hours
- T wave inverts after 24-48 hours
- After 1st week T gets upright
Myocardial Injury
Zone of Injury: nonfunctional area around infarct
- indicates acute MI
- ST Elevation >1mm
- ST segment normal by 72 hours
Myocardial Infarct
Zone of necrosis: irreversible damage at center of MI
- significant Q wave >0.04 sec (any lead but III & aVr)
- w/n 48 hours & never go away
EKG with MI
- Significant Q wave (>0.04 sec)
- occur w/n 48 hours
- never goes away
EKG with Myocardial Ischemia
- incr T wave; peaked and symmetrical
- initially & for 1st several hours
- 24-48 hours after MI: T wave inverts
- becomes upright after 1st week
EKG with Myocardial Injury
- ST segment elevation
- > 1mm over baseline (2 small boxes)
- immediately
- returned to normal by 72 hours
Potassium
resting membrane potential
Calcium
threshold potential
Low K+
-membrane potential lower
High K+
-membrane potential higher
Low Ca++
-threshold potential lower
High Ca++
-threshold potential higher
Trousseau sign
- (hypocalcemia)
- contraction of hand and fingers with the arterial blood flow of arm occluded for 5 min
Chvostek Sign
- hypocalcemia
- tap facial nerve below temple and nose/lip twitches
EKG with subendocardial MI
- ST segment depression
- Inverted T wave (deep and symmetrical)
Normal Magnesium Levels
- 1.8-3.0 mg/dL
1. 5-2.5 mEq/L
Hypomagnesia
- alcoholics or result of multiple electrolyte abnormalities
- can lead to myocardial irritability, A-fib, PVC
Subendocardial MI
(Non-Q wave MI)
- partial thickness (inner portion)
- necrosis is patchy
- due to relative insufficiency of coronary blood flow
- ST seg depression
- Inverted T waves
ST Segment depression
-Occurs with subencdocardial MI, K+ deficiency, digitalis toxicity with ex’s (if ischemic)
Normal K+ levels
3.5-5.3 mEq/L
Normal Ca++ Levels
- 8.2-10.4 mg/dL
4. 5-5.5 mEq/L
Hypercalcemia
- raises threshold potential (decreased excitability)
- EKG: shortened QRS, depressed T waves
–>heart block
Hypocalcemia
- lowers threshold potential (easier to excite)
- EKG: prolonged QT interval
–>ventricular arrhythmia & cardiac arrest
Causes of Hypercalcemia
- thiazide diuretic use
- acidosis
- adrenal insufficiency
- immobility
- vitamin D excess
Causes of Hyperkalemia
- endocrine problems
- renal problems
- result of K+ replacement/overdose
Causes of Hypokalemia
- use of diuretics
- vomiting
- diarrhea
- sweating
- alkalosis
Causes of Hypocalcemia
- multiple transfusion of titrated blood
- renal failure
- alkalosis
- laxatives
- antacid abuse
- parathyroid damage/removal
Hyperkalemia
- cell membrane hypopolarized (easier to stim)
- EKG: narrow, tall T waves, shorter QT interval
- EKG severe: ST seg depression, prolonged PR, wide QRS
–>v fib or cardiac arrest
Hypokalemia
- cell membrane becomes hyperpolarized (harder to excite)
- EKG: decr T wave amplitude, ST seg depression, P wave peaked, QRS prolonged
–>ventricular arrhythmias
Symptoms of Hypercalcemia
- fatigue
- weakness
- lethargy
- anorexia
- impaired renal function
- nausea
- constipation
Symptoms of Hypocalcemia
- confusion
- paresthesia (mouth, digits)
- Carpal spasm
- hyperreflexia
Anterior Infarct
V2, V3 (V4 with greater damage)
Blood Supply: LAD
Anteroseptal Infarct
V1, V2, V3
Blood Supply: LAD
Anterolateral Infarct
-V4, V5, V6, I, aVL
Blood: LAD & Circumflex
Septal Infarct
-Leads V1, V2
Blood: LAD
Lateral Infarct
I, aVL, V5, V6
Blood: circumflex
Inferior Infarct
II, III, aVF
Blood: RCA
Inferolateral Infarct
-II, III, aVF, V5, V6
Blood: RCA & Circumflex
Posterior Infarct
V1, V2, V3
Blood: posterior descending