Cardiovascular Lab Tests Flashcards
1
Q
Enzymes with Suspected MI
A
- creatine phosphokinase
- lactate dehydrogenase
- aspartate aminotransferase
2
Q
Isoenzymes
A
- subtypes of broken down enxymes
- ex. CK-MB, LDH1
3
Q
5 LDH Isoenzymes
A
-LDH1-LDH5
4
Q
Cardiac Markers
A
- enzymes
- Mm proteins
5
Q
Enzymes
A
- some are organ specific & get released with organ is damaged
- blood serum analyzed to detect presence of increased enzyme levels
-determine amount & time of damage
6
Q
Muscle Proteins
A
- Troponin
- Myoglobin
7
Q
3 CK Isoenzymes
A
- CK-MB (heart)
- CK-MM (muscle)
- CK-BB (brain)
8
Q
Hb Normal Values
A
- male: 14-18 g/dL
- female: 13-16 g/dL
9
Q
Ballpark CK Value Interpretation
A
5-75 Normal 200-400 Small MI 400-800 Med MI >800 Large MI >2000 very large MI
10
Q
Myoglobin
A
- O2 binding heme protein
- found in cytosol of striated Mm
- Upper limit of reference interval: 70 microgram/L
11
Q
CK-MB Mass
A
- measures protein concentration of CK-MB
- Elevates sooner than CK or CK-MB
12
Q
Blood Analysis
A
- Hb
- Hct
- Leukocytes
- Platelets
13
Q
Hct
A
-% of volume of blood that consists of RBC
the rest is plasma
14
Q
Clotting Measurements
A
- PT
- PTT
- INR
15
Q
INR
A
- method to standardize between labs
- normal: 0.9-1.1
- therapeutic: 1.5-2.5
-Increased #=slower to clot
