Cardiopulmonary Pharmacology Flashcards
1
Q
Types of Adrenergic receptors
A
- Beta1
- Beta2
- Alpha1
- Alpha2
2
Q
Adrenergic Receptors
A
- Released by post ganglionic sympathetic neurons
- Types (B1, B2, A1, A2)
- Neurotransmitters (NE, E)
3
Q
Adrenergic Neurotransmitters
A
- Norepinephrine
- Epinephrine
4
Q
Nicotinic Receptors
A
- post ganglionic neuron transmission
- muscle contraction
5
Q
2 Cholinergic Receptors
A
- muscarinic
- nicotinic
6
Q
Muscarinic Receptors cause:
A
-decrease HR (SA, AV & atria)
7
Q
Anti-Anginal Drugs Work by:
A
- decreasing myocaridal oxygen demand
- increasing myocardial oxygen supply
8
Q
Beta Blocker Endings
A
-olol
9
Q
S=
A
-Selective
Beta1 receptor only
10
Q
NS=
A
Nonselective
beta1 and beta2 receptors
11
Q
Alpha1
A
- many target organs (blood vessels)
- smooth muscle contraction
- increases force of heart contraction
12
Q
Alpha2
A
- many target organs
- contracts some smooth muscle
- presynaptic of NE release
- inhibition of lipolysis
13
Q
Beta1
A
- acts on Heart and fat cells
- increases HR
- incr force of heart contraction
- increase lipolysis
14
Q
Beta2
A
- on smooth muscle and ducts
- Smooth muscle relaxation
- K+ uptake (skel Mm)
- glycogenolysis (liver)
15
Q
Pharmacological Management
A
- anti-anginals
- heart failure drugs
- antiarrhythmias
- vasopressors
16
Q
2 Positive Inotropes
A
- cardiac glycosides
- sympathomimetics
17
Q
8 Hypertensive Drug Types
A
- diuretics
- noradrenergics
- alpha adrenergic blockers
- centrally acting agents
- ACE inhibitors
- Beta blockers
- Ca++ channel blockers
- Angiotensin II receptor blockers
18
Q
-Antiarrythmics
A
- Class I: Na+ channel blockers
- Class II: Beta blockers
- Class III: prolong repolarization
- Class IV: Ca++ channel blockers
- Digitalis
19
Q
6 Anti-Anginal Drugs
A
- Beta blockers
- Nitrates
- Ca++ channel blockers
- Thrombolytics
- Antiplatelets
- Anticoagulants
(Beta blockers & Nitrates decrease O2 demand; rest increase O2 supply)
20
Q
6 Heart Failure Drugs
A
- diuretics
- positive inotropes
- ACE inhibitors
- vasodilators
- beta blockers
- morphine
21
Q
5 Vasopressors
A
- Isopeterenol
- dopamin
- dobutamine
- epinephrine
- NE (Levofed)
