MHC (Exam 1) Flashcards
What are the only thing T cells can recognize?
short linear peptides
A T cell can only recognize its specific antigen. What two things need to be correct for it to recognize and respond?
- correct MHC molecule
- correct peptide
Term for the fact that T cell can only recognize antigen when it has the correct MHC molecule and peptide.
MHC restriction
(T/F) T cells can recognize and respond to antigen with MHC interaction.
False
What are APCs?
antigen-presenting cells
What are the 3 types of professional antigen-presenting cells?
- dendritic cells
- macrophages
- B cells
Dendritic cells act as APCs when they take up antigen and express ________ which is the second signal for an adaptive immune response to occur.
costimulatory molecule (B7)
Term for process of APCs to help T cells become activated.
co-stimulation
_______ is often added with vaccines to allow for a greater response of protection and activation of T cells.
adjuvant