MG

Question 1

muscle weakness improves by

Answer 1

rest (worsened by activity) – worsen by increased activity

Question 2

very common s/s

Answer 2

dipolpia and ptosis (drooping of eyelids)

Question 3

generalized weakness can affect intercostal muscles

Answer 3

respiratory failure

Question 4

risk factos for MG

Answer 4

associated with hx of: RA, SLE, sclera derma

Question 5

triggering

Answer 5

any infection, stress, pregnancy, elevated body temperature (sun bathing/hot tubs)

Question 6

acetylcholinesterase

Answer 6

enzyme that breaks acetylcholine

Question 7

acetylcholinesterase inhibitor (aka cholinesterase inhibitor)

Answer 7

inhibits the breakdown of acetylcholinesterase from breaking down acetylcholine

Question 8

anti-cholinesterase - drug class

Answer 8

classification of drug that decreases the breakdown of acetylcholine – makes sure there is more acetylcholine present

Question 9

health teaching for cytotoxic medication

Answer 9

therapeutic effect may be evident after 3-12 months ; therefore it won’t work during an emergency

Question 10

what medication is used to treat exacerbation

Answer 10

IVIG

Question 11

difference b/w IVIG and TPE

Answer 11

IVIG will destroy antibodies, TPE cleans the blood

Question 12

last resort management for MG

Answer 12

thymectomy

Question 13

Thymectomy

Answer 13

Done to patients younger than 65 years of age with MG diagnosed within the past 3 years; Only treatment that results to complete remission; improvement may occur several months to several years after surgery

Question 14

Myasthenic crisis (exacerbation)

Answer 14

pt having stress or taking inadequate amt of cholinesterase inhibitors
s/s : respiratory distress; dysphagia; dysarthria; ptosis; diplopia; prominent muscle weakness

Question 15

Cholinergic crisis

Answer 15

patient is taking too much cholinesterase inhibitor (overmedication)

Answer 16

Hx of the patient for example

if pt is refusing the medication then –> muastjenoc crisis

Question 17

if we give tensilon and s/s disappear it’s

Answer 17

myasthenic crisis

Question 18

if we give atrofine and