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Bioengineering approaches to cancer > Metastasis II > Flashcards

Metastasis II Flashcards

1
Q

What do high EMT-TFs correlate with?

A

Worse survival rates

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2
Q

What is the relation between the states of EMT in a cancerous cell?

A

E vs M spectrum

Not binary

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3
Q

What is the difference between circulating tumour cells and circulating tumour microemboli?

A

CTMs are more successful in creating metastasis then CTCs

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4
Q

What can extracellular vesicles contain?

A

Microvesicles
Exosomes
Apoptotic bodies
Oncosomes

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5
Q

What are the roles of extracellular vesicles on metastasis?

A

Promotion of angiogenesis

Aid in premetastatic niche formation (i.e. through inflammation)

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Bioengineering approaches to cancer (13 decks)

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